Roles of mTOR complexes in the kidney: implications for renal disease and transplantation

D Fantus, NM Rogers, F Grahammer… - Nature Reviews …, 2016 - nature.com
The mTOR pathway has a central role in the regulation of cell metabolism, growth and
proliferation. Studies involving selective gene targeting of mTOR complexes (mTORC1 and …

Diagnosis of acute kidney injury using functional and injury biomarkers: workgroup statements from the tenth Acute Dialysis Quality Initiative Consensus Conference

PA McCullough, AD Shaw, M Haase… - ADQI consensus on AKI …, 2013 - karger.com
Acute kidney injury (AKI) commonly occurs in hospitalized patients and is independently and
strongly associates with morbidity and mortality. The clinical benefits of a timely and …

ESPEN guideline on clinical nutrition in hospitalized patients with acute or chronic kidney disease

E Fiaccadori, A Sabatino, R Barazzoni, JJ Carrero… - Clinical Nutrition, 2021 - Elsevier
Acute kidney disease (AKD)-which includes acute kidney injury (AKI)–and chronic kidney
disease (CKD) are highly prevalent among hospitalized patients, including those in …

[HTML][HTML] Klotho deficiency is an early biomarker of renal ischemia–reperfusion injury and its replacement is protective

MC Hu, M Shi, J Zhang, H Quiñones, M Kuro-o… - Kidney international, 2010 - Elsevier
Klotho is an antiaging substance with pleiotropic actions including regulation of mineral
metabolism. It is highly expressed in the kidney and is present in the circulation and urine …

Biological markers of acute kidney injury

ED Siew, LB Ware, TA Ikizler - Journal of the American Society of …, 2011 - journals.lww.com
An abrupt change in serum creatinine, the most common indicator of acute kidney injury
(AKI), is strongly linked to poor outcomes across multiple clinical settings. Despite endless …

Epidemiology of acute kidney injury

J Cerda, N Lameire, P Eggers, N Pannu… - Clinical journal of the …, 2008 - journals.lww.com
Epidemiology of Acute Kidney Injury : Clinical Journal of the American Society of Nephrology
Epidemiology of Acute Kidney Injury : Clinical Journal of the American Society of Nephrology …

The contrasting characteristics of acute kidney injury in developed and developing countries

J Cerdá, A Bagga, V Kher… - Nature clinical practice …, 2008 - nature.com
Acute kidney injury (AKI) has become increasingly prevalent in both developed and
developing countries, and is associated with severe morbidity and mortality, especially in …

Predictors of recurrent AKI

ED Siew, SK Parr, K Abdel-Kader… - Journal of the …, 2016 - journals.lww.com
Recurrent AKI is common among patients after hospitalized AKI and is associated with
progressive CKD. In this study, we identified clinical risk factors for recurrent AKI present …

Early diagnosis of acute kidney injury: the promise of novel biomarkers

SS Soni, C Ronco, N Katz, DN Cruz - Blood purification, 2009 - karger.com
The incidence of acute kidney injury (AKI) formerly referred to as acute renal failure (ARF) is
increasing to epidemic proportions. Development of AKI portends excessive morbidity and …

Acute kidney injury in the elderly

K Abdel-Kader, PM Palevsky - Clinics in geriatric medicine, 2009 - geriatric.theclinics.com
Acute renal failure (ARF) is the rapid loss of kidney function, occurring over hours or days
and resulting in the accumulation of metabolic waste products and the dysregulation of …