Bufalin for an innovative therapeutic approach against cancer
L Soumoy, GE Ghanem, S Saussez, F Journe - Pharmacological Research, 2022 - Elsevier
Bufalin is an endogenous cardiotonic steroid, first discovered in toad venom but also found
in the plasma of healthy humans, with anti-tumour activities in different cancer types. The …
in the plasma of healthy humans, with anti-tumour activities in different cancer types. The …
Toad venom: A comprehensive review of chemical constituents, anticancer activities, and mechanisms
FJ Li, JH Hu, X Ren, CM Zhou, Q Liu… - Archiv der …, 2021 - Wiley Online Library
Toad venom, a traditional natural medicine, has been used for hundreds of years in China
for treating different diseases. Many studies have been performed to elucidate the …
for treating different diseases. Many studies have been performed to elucidate the …
Anticancer and antiviral properties of cardiac glycosides: a review to explore the mechanism of actions
Cardiac glycosides (CGs) have a long history of treating cardiac diseases. However, recent
reports have suggested that CGs also possess anticancer and antiviral activities. The …
reports have suggested that CGs also possess anticancer and antiviral activities. The …
New therapeutic aspects of steroidal cardiac glycosides: the anticancer properties of Huachansu and its main active constituent Bufalin
C Cheng, J Wang, J Chen, KT Kuo, J Tang… - Cancer Cell …, 2019 - Springer
Aim of the review In the past decade, increasing research attention investigated the novel
therapeutic potential of steroidal cardiac glycosides in cancer treatment. Huachansu and its …
therapeutic potential of steroidal cardiac glycosides in cancer treatment. Huachansu and its …
Therapeutic potential of targeting membrane-spanning proteoglycan SDC4 in hepatocellular carcinoma
H Yang, Y Liu, MM Zhao, Q Guo, XK Zheng, D Liu… - Cell Death & …, 2021 - nature.com
Abstract Syndecan-4 (SDC4) functions as a major endogenous membrane-associated
receptor and widely regulates cytoskeleton, cell adhesion, and cell migration in human …
receptor and widely regulates cytoskeleton, cell adhesion, and cell migration in human …
Chinese medicines for prevention and treatment of human hepatocellular carcinoma: current progress on pharmacological actions and mechanisms
Hepatocellular carcinoma (HCC) is one of leading causes of death in the world. Although
various treatments have been developed, the therapeutic side effects are far from desirable …
various treatments have been developed, the therapeutic side effects are far from desirable …
[HTML][HTML] Bufalin suppresses hepatocellular carcinoma invasion and metastasis by targeting HIF-1α via the PI3K/AKT/mTOR pathway
H Wang, C Zhang, L Xu, K Zang, Z Ning, F Jiang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
It has been reported that there are multiple mechanisms by which bufalin could exert its
antimetastatic effect. HIF-1α has been reported to be involved in tumor migration and …
antimetastatic effect. HIF-1α has been reported to be involved in tumor migration and …
A green approach for enhancing oxidation stability including long storage periods of biodiesel via Thuja oreantalis L. as an antioxidant additive
In this study, we evaluated leaf extract of Thuja oreantalis L. as a natural antioxidant additive
for biodiesel oxidation stability enhancement. Primarily the total phenolic content has been …
for biodiesel oxidation stability enhancement. Primarily the total phenolic content has been …
Prospects and therapeutic applications of cardiac glycosides in cancer remediation
Active metabolites from natural sources are the predominant molecular targets in numerous
biological studies owing to their appropriate compatibility with biological systems and …
biological studies owing to their appropriate compatibility with biological systems and …
Recent progress in understanding the action of natural compounds at novel therapeutic drug targets for the treatment of liver cancer
Y Zheng, W Zhang, L Xu, H Zhou, M Yuan… - Frontiers in …, 2022 - frontiersin.org
Liver cancer is the third most common cause of cancer-related death following lung and
stomach cancers. As a highly lethal disease, liver cancer is diagnosed frequently in less …
stomach cancers. As a highly lethal disease, liver cancer is diagnosed frequently in less …