Peptides Are Cardioprotective Drugs of the Future: The Receptor and Signaling Mechanisms of the Cardioprotective Effect of Glucagon-like Peptide-1 Receptor …

AA Boshchenko, LN Maslov… - International Journal of …, 2024 - mdpi.com
The high mortality rate among patients with acute myocardial infarction (AMI) is one of the
main problems of modern cardiology. It is quite obvious that there is an urgent need to …

The role of β‐adrenergic receptors in the regulation of cardiac tolerance to ischemia/reperfusion. Why do β‐adrenergic receptor agonists and antagonists protect the …

LN Maslov, NV Naryzhnaya… - Fundamental & …, 2024 - Wiley Online Library
Background Catecholamines and β‐adrenergic receptors (β‐ARs) play an important role in
the regulation of cardiac tolerance to the impact of ischemia and reperfusion. This systematic …

[PDF][PDF] 尼可地尔对急性ST 段抬高型心肌梗死患者Tp-Te 间期和Tp-Te/QT 以及预后的影响

杨月霞, 刘中慧, 王怀新 - 临床急诊杂志, 2023 - lcjzen.whuhzzs.com
目的: 分析尼可地尔对急性ST 段抬高型心肌梗死(ST-segmentelevation myocardialinfarction,
STEMI) 患者Tp-Te 间期, Tp-Te/QT 及预后的影响. 方法: 选取2021 年9 月—2023 年1 …

[HTML][HTML] Nicorandil alleviates cardiac microvascular ferroptosis in diabetic cardiomyopathy: Role of the mitochondria-localized AMPK-Parkin-ACSL4 signaling pathway

Z Chen, S Li, M Liu, M Yin, J Chen, Y Li, Q Li… - Pharmacological …, 2024 - Elsevier
Mitochondria-associated ferroptosis exacerbates cardiac microvascular dysfunction in
diabetic cardiomyopathy (DCM). Nicorandil, an ATP-sensitive K+ channel opener, protects …

Erucin Exerts Cardioprotective Effects on Ischemia/Reperfusion Injury through the Modulation of mitoKATP Channels

L Flori, R Montanaro, E Pagnotta, L Ugolini, L Righetti… - Biomedicines, 2023 - mdpi.com
Modulation of mitochondrial K channels represents a pharmacological strategy to promote
cardioprotective effects. Isothiocyanates emerge as molecules capable of releasing …

δ-Opioid Receptor as a Molecular Target for Increasing Cardiac Resistance to Reperfusion in Drug Development

NV Naryzhnaya, AV Mukhomedzyanov, M Sirotina… - Biomedicines, 2023 - mdpi.com
An analysis of published data and the results of our own studies reveal that the activation of
a peripheral δ2-opioid receptor (δ2-OR) increases the cardiac tolerance to reperfusion. It …

Angiotensin 1–7 increases cardiac tolerance to ischemia/reperfusion and mitigates adverse remodeling of the heart—The signaling mechanism

IA Derkachev, SV Popov, LN Maslov… - Fundamental & …, 2024 - Wiley Online Library
Background The high mortality rate of patients with acute myocardial infarction (AMI)
remains the most pressing issue of modern cardiology. Over the past 10 years, there has …