Glutathione (GSH) is an important member of cellular antioxidative system. In cancer cells, a
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …

Glutathione (GSH), the main redox buffer, has long been recognized as a pivotal modulator
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …

Reactive oxygen species (ROS), a class of highly bioactive molecules, have been widely
studied in various types of cancers. ROS are considered to be normal byproducts of …

The growing interest in nanomedicine over the last 20 years has carved out a research field
called “nanocatalytic therapy,” where catalytic reactions mediated by nanomaterials are …

Smoking is a major risk factor for a variety of diseases, including cancer and immune-
mediated inflammatory diseases. Tobacco smoke contains a mixture of chemicals, including …

Applying Fenton chemistry in the tumor microenvironment (TME) for cancer therapy is the
most significant feature of chemodynamic therapy (CDT). Owing to the mild acid and …

Reactive oxygen species (ROS) are by‐products of normal cell activity. They are produced
in many cellular compartments and play a major role in signaling pathways. Overproduction …

Chemodrug resistance is a major reason accounting for tumor recurrence. Given the
mechanistic complexity of chemodrug resistance, molecular inhibitors and targeting drugs …

Although the serum-abundant metal-binding protein transferrin (encoded by the Trf gene) is
synthesized primarily in the liver, its function in the liver is largely unknown. Here, we …

Chemotherapy is a well-known and effective treatment for different cancers; unfortunately, it
has not been as efficient in the eradication of all cancer cells as been expected. The …