Nano-based eye drop: Topical and noninvasive therapy for ocular diseases

C Wang, Y Pang - Advanced drug delivery reviews, 2023 - Elsevier
Eye drops are the most accessible therapy for ocular diseases, while inevitably suffering
from their lower bioavailability which highly restricts the treatment efficacy. The introduction …

Functional nano-systems for transdermal drug delivery and skin therapy

L Liu, W Zhao, Q Ma, Y Gao, W Wang, X Zhang… - Nanoscale …, 2023 - pubs.rsc.org
Transdermal drug delivery is one of the least intrusive and patient-friendly ways for
therapeutic agent administration. Recently, functional nano-systems have been …

Tailoring the multi-functional properties of phospholipids for simple to complex self-assemblies

T Waghule, RN Saha, A Alexander, G Singhvi - Journal of Controlled …, 2022 - Elsevier
The unique interfacial properties, huge diversity, and biocompatible nature of phospholipids
make them an attractive pharmaceutical excipient. The amphiphilic nature of these …

Psoriasis: pathological mechanisms, current pharmacological therapies, and emerging drug delivery systems

VK Rapalli, T Waghule, S Gorantla, SK Dubey… - Drug Discovery …, 2020 - Elsevier
Highlights•Psoriasis pathogenesis involved cytokines, microbial peptides, genetic
disposition.•Psoriasis is autoimmune disorder that affects approximately 125 million …

Dermatokinetic assessment of luliconazole-loaded nanostructured lipid carriers (NLCs) for topical delivery: QbD-driven design, optimization, and in vitro and ex vivo …

A Mahmood, VK Rapalli, S Gorantla, T Waghule… - Drug Delivery and …, 2022 - Springer
The present study is concerned with the QbD-based design and development of
luliconazole-loaded nanostructured lipid carriers (NLCs) hydrogel for enhanced skin …

Solid lipid nanocarriers embedded hydrogel for topical delivery of apremilast: In-vitro, ex-vivo, dermatopharmacokinetic and anti-psoriatic evaluation

VK Rapalli, S Sharma, A Roy, A Alexander… - Journal of Drug Delivery …, 2021 - Elsevier
The present work aimed to develop topical solid lipid nanocarriers (SLN) loaded hydrogel of
apremilast (API) for psoriasis therapy to minimize the systemic adverse effects. The quality …

The role of microRNA in psoriasis: A review

X Jiang, R Shi, R Ma, X Tang, Y Gong… - Experimental …, 2023 - Wiley Online Library
Psoriasis is a chronic immune‐mediated inflammatory skin disease that involves a complex
interplay between infiltrated immune cells and keratinocytes. Great progress has been made …

Nanostructured lipid carriers of essential oils as potential tools for the sustainable control of insect pests

S Tortorici, C Cimino, M Ricupero, T Musumeci… - Industrial Crops and …, 2022 - Elsevier
Plant essential oils (EOs) represent a promising alternative and sustainable tool to reduce
the negative environmental impact of conventional management systems, eg, synthetic …

Luliconazole loaded lyotropic liquid crystalline nanoparticles for topical delivery: QbD driven optimization, in-vitro characterization and dermatokinetic assessment

A Mahmood, VK Rapalli, T Waghule, S Gorantla… - Chemistry and physics …, 2021 - Elsevier
Fungal infections are an important cause of morbidity and pose a serious health concern
especially in immunocompromised patients. Luliconazole (LUL) is a topical imidazole …

Potential of lipid-based nanocarriers against two major barriers to drug delivery—skin and blood–brain barrier

MS Khan, S Mohapatra, V Gupta, A Ali, PP Naseef… - Membranes, 2023 - mdpi.com
Over the past few years, pharmaceutical and biomedical areas have made the most
astounding accomplishments in the field of medicine, diagnostics and drug delivery …