[HTML][HTML] The role of BDNF in multiple sclerosis neuroinflammation

V Nociti, M Romozzi - International Journal of Molecular Sciences, 2023 - mdpi.com
Multiple sclerosis (MS) is a chronic, inflammatory, and degenerative disease of the central
nervous system (CNS). Inflammation is observed in all stages of MS, both within and around …

Function of neurotrophic factors beyond the nervous system: inflammation and autoimmune demyelination

R Linker, R Gold, F Luhder - Critical Reviews™ in Immunology, 2009 - dl.begellhouse.com
In the nervous system, neurotrophic factors play a role during development, especially for
the differentiation of neuronal and glial cells. Moreover, they promote cell survival of …

Therapeutic role of beta-interferons in multiple sclerosis

A Javed, AT Reder - Pharmacology & therapeutics, 2006 - Elsevier
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS). In
the last 12 years, there has been a proliferation of studies elucidating the immune …

[HTML][HTML] Increased plasma levels of brain derived neurotrophic factor (BDNF) after multiple sclerosis relapse

ERC Frota, DH Rodrigues, EA Donadi, DG Brum… - Neuroscience …, 2009 - Elsevier
Brain derived neurotrophic factor (BDNF) has been related to neuroprotection in a series of
central nervous system diseases, although its role in multiple sclerosis (MS) was only …

The role of growth factors as a therapeutic approach to demyelinating disease

Y Huang, CF Dreyfus - Experimental neurology, 2016 - Elsevier
A variety of growth factors are being explored as therapeutic agents relevant to the axonal
and oligodendroglial deficits that occur as a result of demyelinating lesions such as are …

Production of brain-derived neurotrophic factor by mononuclear cells of patients with multiple sclerosis treated with glatiramer acetate, interferon-β 1a, and high doses …

P Sarchielli, M Zaffaroni, A Floridi… - Multiple Sclerosis …, 2007 - journals.sagepub.com
Sixty, relapsing remitting (RR) multiple sclerosis (MS) patients, who underwent treatment
with glatiramer acetate (GA), interferon (IFN)-β 1a, and immunoglobulins (Igs)(20 per …

[HTML][HTML] The role of neurotrophins in multiple sclerosis—pathological and clinical implications

A Kalinowska-Lyszczarz, J Losy - International journal of molecular …, 2012 - mdpi.com
Multiple sclerosis (MS) is a chronic inflammatory demyelinating and neurodegenerative
disease of the central nervous system (CNS) with unknown etiology. It was recently …

Brain-derived neurotrophic factor and TrkB receptor in experimental autoimmune encephalomyelitis and multiple sclerosis

L De Santi, P Annunziata, E Sessa… - Journal of the neurological …, 2009 - Elsevier
The interaction between the immune and nervous systems can be both detrimental and
beneficial. Experimental autoimmune encephalomyelitis (EAE) is an animal model of …

[HTML][HTML] Exploring the mRNA and Plasma Protein Levels of BDNF, NT4, SIRT1, HSP27, and HSP70 in Multiple Sclerosis Patients and Healthy Controls

I Sokolowski, A Kucharska-Lusina, E Miller… - International Journal of …, 2023 - mdpi.com
Multiple sclerosis (MS) is a chronic, autoimmune neurodegenerative disease affecting the
central nervous system. It is a major cause of non-traumatic neurological disability among …

Protective autoimmunity in the nervous system

JJ Graber, S Dhib-Jalbut - Pharmacology & therapeutics, 2009 - Elsevier
The immune system can play both detrimental and beneficial roles in the nervous system.
Multiple arms of the immune system, including T cells, B cells, NK cells, mast cells …