Alzheimer disease (AD) is a frequent and devastating neurodegenerative disease in
humans, but still no curative treatment has been developed. Although many explicative …

By 2050, the aging population is predicted to expand by over 100%. Considering this rapid
growth, and the additional strain it will place on healthcare resources because of age …

Objective Increased inflammation and oxidative stress have been shown in Major
Depressive Disorder (MDD), although there is significant heterogeneity across studies …

Astrocytes activation in response to stroke results in altered mitochondrial exchange with
neurons. Ginsenoside Rb1is a major ginsenoside of Panax ginseng particularly known for …

Alzheimer's disease (AD) is one of the foremost neurodegenerative diseases, characterized
by beta-amyloid (Aβ) plaques and significant progressive memory loss. In AD, astrocytes are …

Understanding the role of astrocytes in the central nervous system has changed dramatically
over the last decade. The accumulating findings indicate that glial cells are involved not only …

Aging is a process characterized by cognitive impairment and mitochondrial dysfunction. In
neurons, these organelles are classified as synaptic and non-synaptic mitochondria …

As the most abundant cell types in the brain, astrocytes form a tissue-wide signaling network
that is responsible for maintaining brain homeostasis and regulating various brain activities …

Growing evidence indicates that astrocytes are tightly connected to Alzheimer's disease
(AD) pathogenesis. However, the way in which astrocytes participate in AD initiation and …

Astrocytes are highly specialised cells, responsible for CNS homeostasis and neuronal
activity. Lack of human in vitro systems able to recapitulate the functional changes affecting …