Redox and mTOR-dependent regulation of plasma lamellar calcium influx controls the senescence-associated secretory phenotype
A Chandrasekaran, MY Lee, X Zhang… - Experimental …, 2020 - journals.sagepub.com
Cellular senescence has evolved as a protective mechanism to arrest growth of cells with
oncogenic potential but is accompanied by the often pathologically deleterious senescence …
oncogenic potential but is accompanied by the often pathologically deleterious senescence …
Analytical and structural investigation via infrared spectroscopy and density functional methods of cuprous complexes of the antioxidant tripeptide glutathione (GSH) …
A copper (I) compound of reduced glutathione (Glu, S; Cys, R)-(GSH) was isolated from the
reaction of Cu I Cl and zwitterionic H 3 GSH (+−) in acetonitrile: water medium. The …
reaction of Cu I Cl and zwitterionic H 3 GSH (+−) in acetonitrile: water medium. The …
[HTML][HTML] In vitro P38MAPK inhibition in aged astrocytes decreases reactive astrocytes, inflammation and increases nutritive capacity after oxygen-glucose deprivation
M Revuelta, A Elicegui, T Scheuer… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Proper astroglial functioning is essential for the development and survival of neurons and
oligodendroglia under physiologic and pathological circumstances. Indeed, malfunctioning …
oligodendroglia under physiologic and pathological circumstances. Indeed, malfunctioning …
Succinate dehydrogenase complex subunit C: Role in cellular physiology and disease
Q Wang, M Li, N Zeng, Y Zhou… - Experimental Biology and …, 2023 - journals.sagepub.com
Succinate dehydrogenase complex subunit C (SDHC) is a subunit of mitochondrial complex
II (MCII), which is also known as succinate dehydrogenase (SDH) or succinate: ubiquinone …
II (MCII), which is also known as succinate dehydrogenase (SDH) or succinate: ubiquinone …
Protective effects of noradrenaline on benzo [a] pyrene-induced oxidative stress responses in brain tumor cell lines
M Patri, A Singh - In Vitro Cellular & Developmental Biology-Animal, 2019 - Springer
Abstract Benzo [a] pyrene (B [a] P) is an ubiquitous environmental pollutant that is generated
during combustion of fossil fuels. We examine the effect of noradrenaline (NA) on B [a] P …
during combustion of fossil fuels. We examine the effect of noradrenaline (NA) on B [a] P …
Combination effect of exercise training and eugenol supplementation on the hippocampus apoptosis induced by chlorpyrifos
S Nikbin, A Derakhshideh, F Kanozi… - Molecular Biology …, 2020 - Springer
The aim of this study was to investigate the combination effect of exercise training and
eugenol supplementation on the hippocampus apoptosis induced by CPF. 64 adult male …
eugenol supplementation on the hippocampus apoptosis induced by CPF. 64 adult male …
Role of autophagy in HIV-1 and drug abuse-mediated neuroinflammaging
Chronic low-grade inflammation remains an essential feature of HIV-1 infection under
combined antiretroviral therapy (cART) and contributes to the accelerated cognitive defects …
combined antiretroviral therapy (cART) and contributes to the accelerated cognitive defects …
An ex vivo approach to assess mitochondrial ROS by flow cytometry in AAV-tagged astrocytes in adult mice
C Vicente-Gutierrez, JP Bolaños - Bio-protocol, 2020 - bio-protocol.org
Mitochondrial reactive oxygen species (mROS) are naturally produced signalling molecules
extremely relevant for understanding both health-and disease-associated biological …
extremely relevant for understanding both health-and disease-associated biological …
Visualizing cancer-originated acetate uptake through MCT1 in reactive astrocytes demarcates tumor border and extends survival in glioblastoma patients
Glioblastoma multiforme (GBM) is a devastating brain tumor with dismal prognosis of only 15-
month survival regardless of surgical resection. Here, we report an advanced neuroimaging …
month survival regardless of surgical resection. Here, we report an advanced neuroimaging …
ECSIT prevents Alzheimer's disease pathology by regulating neuronal mitochondrial ROS and mitophagy
A Lepelley, LS Vaughn, A Staniszewski, H Zhang, F Du… - BioRxiv, 2020 - biorxiv.org
Altered mitochondrial fitness is a potential triggering factor in Alzheimer's disease (AD).
Mitochondrial quality control pathways are dysfunctional and mitochondrially-derived …
Mitochondrial quality control pathways are dysfunctional and mitochondrially-derived …