NLRP3 inflammasome in hepatic diseases: A pharmacological target
E Ramos-Tovar, P Muriel - Biochemical Pharmacology, 2023 - Elsevier
The NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome pathway is
mainly responsible for the activation and release of a cascade of proinflammatory mediators …
mainly responsible for the activation and release of a cascade of proinflammatory mediators …
Natural Products for Acetaminophen-Induced Acute Liver Injury: A Review
X Li, R Lao, J Lei, Y Chen, Q Zhou, T Wang, Y Tong - Molecules, 2023 - mdpi.com
The liver plays a vital role in metabolism, synthesis, and detoxification, but it is susceptible to
damage from various factors such as viral infections, drug reactions, excessive alcohol …
damage from various factors such as viral infections, drug reactions, excessive alcohol …
Drug-induced liver injury and anti-hepatotoxic effect of herbal compounds: a metabolic mechanism perspective
Background Drug-induced liver injury (DILI) is the most challenging and thought-provoking
liver problem for hepatologists owing to unregulated medication usage in medical practices …
liver problem for hepatologists owing to unregulated medication usage in medical practices …
The beneficial effects of l‐carnitine and infliximab in methotrexate‐induced hepatotoxicity: Emphasis on Notch1/Hes‐1 signaling
SM Radwan, GA Abdel‐Latif, SS Abbas… - Archiv der …, 2023 - Wiley Online Library
Methotrexate (MTX)‐induced hepatotoxicity is a serious adverse effect that may limit its use.
Therefore, eligible drugs to ameliorate MTX‐induced hepatotoxicity are required. l‐Carnitine …
Therefore, eligible drugs to ameliorate MTX‐induced hepatotoxicity are required. l‐Carnitine …
Direct targeting of S100A9 with Icariin counteracted acetaminophen‑induced hepatotoxicity
P Shen, M Xue, Z Hu, L Han, X Deng - International Immunopharmacology, 2024 - Elsevier
Acetaminophen (APAP) is a widely used antipyretic and analgesic medication, but its
overdose can induce acute liver failure with lack of effective therapies. Icariin is a bioactive …
overdose can induce acute liver failure with lack of effective therapies. Icariin is a bioactive …
[HTML][HTML] Long-term neurological implications of severe acute respiratory syndrome coronavirus 2 infections in neonates: Innate immune memory and chronic …
T Nobutoki - Medical Hypotheses, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can cause long-
term neurological complications in adults. However, the mechanisms by which early-life …
term neurological complications in adults. However, the mechanisms by which early-life …