Multimorbidity in heart failure: leveraging cluster analysis to guide tailored treatment strategies

MC van de Veerdonk, G Savarese, ML Handoko… - Current Heart Failure …, 2023 - Springer
Abstract Review Purpose This review summarises key findings on treatment effects within
phenotypical clusters of patients with heart failure (HF), making a distinction between …

The spectrum of post-myocardial infarction care: From acute ischemia to heart failure

KH Akhtar, MS Khan, SJ Baron, S Zieroth… - Progress in …, 2024 - Elsevier
Heart failure (HF) is the leading cause of mortality in patients with acute myocardial
infarction (AMI), with incidence ranging from 14% to 36% in patients admitted due to AMI. HF …

Changes in mid‐regional pro‐adrenomedullin during treatment with sacubitril/valsartan

PL Myhre, Y Liu, IJ Kulac, BL Claggett… - European Journal of …, 2023 - Wiley Online Library
Aims Adrenomedullin is a vasodilatory peptide with a role in microcirculatory and
endothelial homeostasis. Adrenomedullin is a substrate for neprilysin and may therefore …

Angiotensin receptor-neprilysin inhibition in patients with STEMI vs NSTEMI

DL Mann, J Nicolas, B Claggett, ZM Miao… - Journal of the American …, 2024 - jacc.org
Background Patients who sustain an acute myocardial infarction (AMI), including ST-
segment elevation myocardial infarction (STEMI) and non–ST-segment elevation myocardial …

Efficacy of early administration of sacubitril/valsartan after coronary artery revascularization in patients with acute myocardial infarction complicated by moderate-to …

H Yin, L Ma, Y Zhou, X Tang, R Li, Y Zhou, J Shi… - Heart and Vessels, 2024 - Springer
Abstract Effects of angiotensin receptor/neprilysin inhibitors (ARNI) on ventricular
remodeling in patients with heart failure, especially heart failure with reduced ejection …

Antiarrhythmic and Anti-Inflammatory Effects of Sacubitril/Valsartan on Post-Myocardial Infarction Scar

D Martínez-Falguera, J Aranyó, A Teis… - Circulation …, 2024 - Am Heart Assoc
BACKGROUND: Sacubitril/valsartan (Sac/Val) is superior to angiotensin-converting enzyme
inhibitors in reducing the risk of heart failure hospitalization and cardiovascular death, but its …

Pharmacological and Device-Based Intervention for Preventing Heart Failure After Acute Myocardial Infarction―A Clinical Review―

Y Saito, Y Kobayashi, K Tsujita, K Kuwahara… - Circulation …, 2024 - jstage.jst.go.jp
In patients with acute myocardial infarction (MI), heart failure (HF) is one of the most common
complications that is associated with a significant burden of mortality and healthcare …

Optimal treatment for post-MI heart failure in rats: dapagliflozin first, adding sacubitril-valsartan 2 weeks later

W Tao, X Yang, Q Zhang, S Bi, Z Yao - Frontiers in Cardiovascular …, 2023 - frontiersin.org
Background Based on previous research, both dapagliflozin (DAPA) and sacubitril-valsartan
(S/V) improve the prognosis of patients with heart failure (HF). Our study aims to investigate …

[HTML][HTML] Renin-angiotensin system inhibitors and non-ST-elevation myocardial infarction outcomes based on left ventricular ejection fraction

YH Kim, AY Her, SW Rha, CU Choi, BG Choi… - Hellenic Journal of …, 2024 - Elsevier
Background We assessed left ventricular ejection fraction (LVEF) to compare the effects of
renin–angiotensin system inhibitors (RASI) in patients with non-ST-segment elevation …

Targeting the Natriuretic Peptide System to Improve Outcomes: PARADISE Lost or Found

JA Udell, DWJ Armstrong - Journal of the American College of Cardiology, 2024 - jacc.org
Two seminal findings in 1981 transformed cardiology. The first was the finding that
recanalization of acutely occluded coronary arteries salvages myocardium 1—a seemingly …