An overview of diagnostic and management strategies for talaromycosis, an underrated disease

SD Zaongo, F Zhang, Y Chen - Journal of Fungi, 2023 - mdpi.com
Underrated and neglected, talaromycosis is a life-threatening fungal disease endemic to the
tropical and subtropical regions of Asia. In China, it has been reported that talaromycosis …

Molecular methodologies for improved polymicrobial sepsis diagnosis

M Doualeh, M Payne, E Litton, E Raby… - International Journal of …, 2022 - mdpi.com
Polymicrobial sepsis is associated with worse patient outcomes than monomicrobial sepsis.
Routinely used culture-dependent microbiological diagnostic techniques have low …

Rapid diagnosis of Talaromyces marneffei infection by metagenomic next-generation sequencing technology in a Chinese cohort of inborn errors of immunity

L Liu, B Sun, W Ying, D Liu, Y Wang, J Sun… - Frontiers in cellular …, 2022 - frontiersin.org
Talaromyces marneffei (T. marneffei) is an opportunistic pathogen. Patients with inborn
errors of immunity (IEI) have been increasingly diagnosed with T. marneffei in recent years …

Metagenomic next-generation sequencing for rapid detection of pulmonary infection in patients with acquired immunodeficiency syndrome

J Zhong, Y Liu, N Luo, Q Wei, Q Su, J Zou, X Wu… - Annals of Clinical …, 2023 - Springer
Background Acquired immunodeficiency syndrome (AIDS) is associated with a high rate of
pulmonary infections (bacteria, fungi, and viruses). To overcome the low sensitivity and long …

Clinical profile, etiology, and outcome of hemophagocytic lymphohistiocytosis associated with histiocytic necrotizing lymphadenitis

KG Zhou, DH Gong, D Peng, ZQ Wang… - World Journal of …, 2023 - Springer
Hemophagocytic lymphohistiocytosis (HLH) is a lifethreatening clinical syndrome
characterized by aberrantly activated macrophages and cytotoxic T cells, leading to multiple …

Determination of Ideal Factors for Early Adoption and Standardization of Metagenomic Next-Generation Sequencing for Respiratory System Infections

L Zhao, CR Formslag, Q Zhang… - Current …, 2024 - ingentaconnect.com
Background: Metagenomic next-generation sequencing (mNGS) demonstrates great
promise as a diagnostic tool for determining the cause of pathogenic infections. The …

Early detection of gram‑negative bacteria using metagenomic next‑generation sequencing in acute respiratory distress syndrome: A case report

R Wang, R Feng, C Xia, F Ruan… - Experimental and …, 2022 - spandidos-publications.com
Metagenomic next‑generation sequencing (mNGS) is an effective method that can be used
for the identification of early pathogens in patients with suspected severe pneumonia …

Lung abscess caused by the anaerobic pathogen Tannerella forsythia

XY Miao, W Yang, S Wang, J Tang… - Respirology Case …, 2024 - Wiley Online Library
Odontogenic infections can spread to the respiratory tract. Despite the known role of
Tannerella forsythia as the primary pathogen in periodontitis, the association between T …

[PDF][PDF] 应用宏基因组二代测序诊断肺脓肿病原4 例并文献复习

梁春婵, 乐伊莎, 李海燕, 徐昌富, 余刚, 温顺航… - 温州医科大学 …, 2023 - xb.wmu.edu.cn
目的: 探讨宏基因组二代测序(mNGS) 技术诊断肺脓肿病原的价值. 方法: 回顾性分析2019 年8
月至2021 年8 月温州医科大学附属第二医院育英儿童医院儿童呼吸科住院的4 …

[PDF][PDF] Detection of respiratory viruses in clinical samples: Exploring next generation sequencing and clinical metagenomics

S Yadav, V Wagh, S Pajai, ASM Joseph, R Jaganathan… - researchgate.net
Respiratory viral infections accounts for more than 4.25 million fatalities each year, making
them the third most common cause of death worldwide. Although the majority of acute …