Asymmetric organocatalysis: an enabling technology for medicinal chemistry

B Han, XH He, YQ Liu, G He, C Peng… - Chemical Society Reviews, 2021 - pubs.rsc.org
The efficacy and synthetic versatility of asymmetric organocatalysis have contributed
enormously to the field of organic synthesis since the early 2000s. As asymmetric …

A comprehensive review of the antibacterial, antifungal and antiviral potential of essential oils and their chemical constituents against drug-resistant microbial …

S Tariq, S Wani, W Rasool, K Shafi, MA Bhat… - Microbial …, 2019 - Elsevier
Essential oils are a complex mixture of odoriferous, volatile organic compounds. There are
an extensive number of published articles which highlight the antimicrobial action of a …

Essential oils and antifungal activity

F Nazzaro, F Fratianni, R Coppola, V De Feo - Pharmaceuticals, 2017 - mdpi.com
Since ancient times, folk medicine and agro-food science have benefitted from the use of
plant derivatives, such as essential oils, to combat different diseases, as well as to preserve …

Antifungals

S Campoy, JL Adrio - Biochemical pharmacology, 2017 - Elsevier
The need for new antifungal agents is undeniable. Current therapeutic choices for the
treatment of invasive fungal infections are limited to three classes of drugs. Most used …

Antifungal resistance in dermatophytes: Recent trends and therapeutic implications

A Khurana, K Sardana, A Chowdhary - Fungal Genetics and Biology, 2019 - Elsevier
Dermatophytoses or tinea refers to superficial fungal infection of keratinized tissues.
Although generally considered easy to treat, recalcitrant infections, presenting as extensive …

Evolutionary Emergence of Drug Resistance in Candida Opportunistic Pathogens

E Ksiezopolska, T Gabaldón - Genes, 2018 - mdpi.com
Fungal infections, such as candidiasis caused by Candida, pose a problem of growing
medical concern. In developed countries, the incidence of Candida infections is increasing …

Recent developments of metal-based compounds against fungal pathogens

Y Lin, H Betts, S Keller, K Cariou… - Chemical Society Reviews, 2021 - pubs.rsc.org
This review provides insight into the rapidly expanding field of metal-based antifungal
agents. In recent decades, the antibacterial resistance crisis has caused reflection on many …

Development of drugs based on imidazole and benzimidazole bioactive heterocycles: recent advances and future directions

M Gaba, C Mohan - Medicinal Chemistry Research, 2016 - Springer
Imidazole and benzimidazole rings are the most important nitrogen-containing heterocycles,
which are widely explored and utilized by the pharmaceutical industry for drug discovery …

Cinnamaldehyde and its derivatives, a novel class of antifungal agents

S Shreaz, WA Wani, JM Behbehani, V Raja, M Irshad… - Fitoterapia, 2016 - Elsevier
The last few decades have seen an alarming rise in fungal infections, which currently
represent a global health threat. Despite extensive research towards the development of …

Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance

MA Ghannoum, LB Rice - Clinical microbiology reviews, 1999 - Am Soc Microbiol
The increased use of antibacterial and antifungal agents in recent years has resulted in the
development of resistance to these drugs. The significant clinical implication of resistance …