Mismatch repair
The concept of mismatch repair (MMR) was formulated independently in 1964 to explain the
removal of brominated nucleotides from DNA as well as gene conversion during genetic …
removal of brominated nucleotides from DNA as well as gene conversion during genetic …
The dam and dcm strains of Escherichia coli—a review
BR Palmer, MG Marinus - Gene, 1994 - Elsevier
The construction of a variety of strains deficient in the methylation of adenine and cytosine
residues in DNA by the methyltransferases (MTases) Dam and Dcm has allowed the study of …
residues in DNA by the methyltransferases (MTases) Dam and Dcm has allowed the study of …
Rate and molecular spectrum of spontaneous mutations in the bacterium Escherichia coli as determined by whole-genome sequencing
Knowledge of the rate and nature of spontaneous mutation is fundamental to understanding
evolutionary and molecular processes. In this report, we analyze spontaneous mutations …
evolutionary and molecular processes. In this report, we analyze spontaneous mutations …
Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage
P Branch, G Aquilina, M Bignami, P Karran - nature, 1993 - nature.com
ACQUIRED resistance to alkylating agents such as N-methyl-N-nitrosourea or N-methyl-N′-
nitro-N-nitrosoguanidine results from the ability to tolerate the potentially cytotoxic …
nitro-N-nitrosoguanidine results from the ability to tolerate the potentially cytotoxic …
The great GATC: DNA methylation in E. coli
F Barras, MG Marinus - Trends in Genetics, 1989 - cell.com
The ratio in the last column represents the level of promoter activity in a dam muta [nt
compm'ed to wild type, Replacement of GATC by GAIT in the gins promotet reduces the ratio …
compm'ed to wild type, Replacement of GATC by GAIT in the gins promotet reduces the ratio …
Escherichia coli mutator genes
JP Horst, T Wu, MG Marinus - Trends in microbiology, 1999 - cell.com
The isolation and characterization of Escherichia coli mutator genes have led to a better
understanding of DNA replication fidelity mechanisms and to the discovery of important DNA …
understanding of DNA replication fidelity mechanisms and to the discovery of important DNA …
Repair of DNA heteroduplexes containing small heterologous sequences in Escherichia coli.
BO Parker, MG Marinus - Proceedings of the National …, 1992 - National Acad Sciences
Plasmid heteroduplexes were constructed that contain 1, 2, 3, 4, or 5 unpaired bases within
the mnt gene. These were used to assess the efficiency of repair of small heterologous …
the mnt gene. These were used to assess the efficiency of repair of small heterologous …
Increased spontaneous mutation and alkylation sensitivity of Escherichia coli strains lacking the ogt O6-methylguanine DNA repair methyltransferase
Escherichia coli expresses two DNA repair methyltransferases (MTases) that repair the
mutagenic O6-methylguanine (O6MeG) and O4-methylthymine (O4MeT) DNA lesions; one …
mutagenic O6-methylguanine (O6MeG) and O4-methylthymine (O4MeT) DNA lesions; one …
mutM, a second mutator locus in Escherichia coli that generates GC----TA transversions
M Cabrera, Y Nghiem, JH Miller - Journal of bacteriology, 1988 - Am Soc Microbiol
Generates G. C > T. A Transversions Page 1 JOURNAL OF BACTERIOLOGY, Nov. 1988,p.
5405-5407 Vol. No. 11 0021-9193/88/115405-03$02.00/0 Copyright © 1988, American Society …
5405-5407 Vol. No. 11 0021-9193/88/115405-03$02.00/0 Copyright © 1988, American Society …
Dominant negative mutator mutations in the mutS gene of Escherichia coli
TH Wu, MG Marinus - Journal of bacteriology, 1994 - Am Soc Microbiol
The MutS protein of Escherichia coli is part of the dam-directed MutHLS mismatch repair
pathway which rectifies replication errors and which prevents recombination between …
pathway which rectifies replication errors and which prevents recombination between …