Abstract Human papillomavirus (HPV)-positive (HPV+) oropharyngeal squamous cell
carcinoma (OPSCC) has one of the most rapidly increasing incidences of any cancer in high …

Oral squamous cell carcinoma (OSCC) is a common malignancy of the head and neck
region. OSCC has a relatively low survival rate and the incidence of the disease is …

Objective Over many decades, studies on histopathological features have not only
presented high-level evidence of contribution for treatment directions and prognosis of oral …

Abstract Background The American Joint Committee on Cancer (AJCC) has changed the
staging system of oral squamous cell carcinoma (OSCC) in the 8th edition of its staging …

Early oral cancer is preferably treated by surgery. Its complete removal is essential for
locoregional control and disease-free survival. Inadequate resection margins require …

Objectives/Hypothesis Adequate surgical resection of early stage oral tongue cancer
provides the best chance at preventing locoregional disease recurrence. Determination of …

The eighth edition of the TNM classification officially introduced “depth of invasion”(DOI) as a
criterion for determining the T stage in tongue squamous cell carcinoma. The DOI is a well …

Objectives Complete resection of tongue cancer is necessary to achieve local control.
Unfortunately, deep resection margins are frequently inadequate. To improve deep margin …

The 8th edition of American Joint Committee on Cancer (AJCC 8th) staging manual
incorporated depth of invasion (DOI) into pT stage of oral cavity cancer. The aim of this study …

The accuracy of magnetic resonance imaging (MRI)-derived depth of invasion (DOI)
compared to histopathological DOI is still controversial. A meta-analysis was performed to …