Numerous studies have indicated that in cancer treatment Chinese herbal medicines in
combination with chemo-or radio-therapy can be used to enhance the efficacy of and …

The human ATP-binding cassette transporter multidrug resistance protein 1 (MRP1),
encoded by ABCC1, was initially identified because of its ability to confer multidrug …

Collagen is a biopolymer found in the animal body. It is one of the most abundant proteins in
the extracellular matrix that provides strength to the skin, joints, and bones in the human …

Traditional Chinese medicine (TCM) has been a major part of healthcare in China, and has
extensively affected medicine and healthcare in surrounding countries over a long period of …

A platinum-based two-drug regimen is currently the standard of care for patients with
advanced non-small-cell lung cancer (NSCLC). However, chemotherapy-induced side …

Herbal medicines are often used in combination with conventional drugs, and this may give
rise to the potential of harmful herb-drug interactions. This paper updates our knowledge on …

ABSTRACT Introduction: Busulfan (Bu) is an alkylating agent with a limited therapeutic
margin and exhibits inter-patient variability in pharmacokinetics (PK). Despite decades of …

Clinical studies and case reports have identified a number of herb-drug interactions
potentiated by the concurrent use of herbal medicines with prescription drugs. The purpose …

Cancer is becoming more prevalent in elderly patient. Due to polypharmacy, older adults
with cancer are predisposed to drug-drug interactions. There is also an increasing interest in …

Fisetin (3, 3', 4', 7-tetrahydroxyflavone), a naturally occurring flavonoid, has been reported to
inhibit proliferation and induce apoptosis in several cancer types. However, its effect on the …