Background: Evidence from case–control studies suggests that increasing dietary folate
intake is associated with a reduced risk of breast cancer. However, large cohort studies have …

Background: B vitamins such as folate, vitamin B-6, and vitamin B-12 are coenzymes that
are important for DNA integrity and stability. Deficiency in these B vitamins may promote …

Multiple nodes in the one‐carbon metabolism pathway play important regulatory roles in
cancer cell growth and tumorigenesis. The specific biological functions of metabolic …

Epidemiological evidence suggests that intake of folate and other B‐vitamins and genetic
variants in the one‐carbon metabolism pathway could influence the risk of breast cancer …

Background Several studies have determined that dietary intake of B vitamins may be
associated with breast cancer risk as a result of interactions between 5, 10 …

Folate and vitamin D have been shown to be influenced by ultraviolet (UV) radiation. UVA
radiation can break down plasma folate, whereas vitamin D can be synthesized in UVB …

Environmental exposures and/or genetic background in Japanese population, which might
contribute to the relatively low breast cancer incidence rates in Japan, have not been …

Epidemiological studies have reported inconsistent findings for the association between B
vitamins and breast cancer (BC) risk. We investigated the relationship between biomarkers …

Cancer cell metabolism differs significantly from the metabolism of non-transformed cells.
This altered metabolic reprogramming mediates changes in the uptake and use of nutrients …

The interconversion of folates by the one-carbon metabolism pathway is essential for the
synthesis of precursors used in DNA synthesis, repair, and methylation. Perturbations in this …