Our purpose was to identify epigenetic markers of breast cancer risk, which can be reliably
measured in peripheral blood and are amenable for large population screening. We used 2 …

Several studies report that breast cancer survivors (BCS) tend to have a poor diet, as fruit,
vegetable, and legume consumption is often reduced, resulting in a decreased intake of …

Promoter-CpG island hypermethylation has been proposed as an alternative mechanism to
inactivate BRCA1 in the breast where somatic mutations of BRCA1 are rare. To better …

Acrylamide, a potential food carcinogen in humans, is biotransformed to the epoxide
glycidamide in vivo. Both acrylamide and glycidamide are conjugated with glutathione …

There are several evidences supporting the role of 5–10 methylenetetrahydrofolate
reductase (MTHFR) gene polymorphisms in breast cancer (BC). Case control association …

Background/Aims: Emerging evidence indicates that microRNA (miR)-340 is downregulated
in various human cancers, suggesting that it acts as a tumor suppressor. The aim of the …

One-carbon metabolism is a network of biological reactions that plays critical role in DNA
methylation and DNA synthesis, and in turn, facilitates the cross-talk between genetic and …

There have been many original and review articles summarizing the impact of nutrition and
diet on breast cancer risk. However, very few consider the implication of genetic background …

We investigated associations among intake of folate, vitamin B2, vitamin B6, vitamin B12,
and polymorphisms of 5, 10-methylenetetrahydrofolate reductase (MTHFR) and methionine …

Global decrease in DNA methylation is a common feature of cancer and is associated with
genomic and chromosomal instability. Retrospective case–control studies have reported that …