Background Concerns regarding the safety of transfused blood have led to the development
of a range of interventions to minimise blood loss during major surgery. Anti‐fibrinolytic …

Studies have shown that antifibrinolytic (aprotinin, tranexamic acid, epsilon-aminocaproic
acid) reduce blood loss in orthopedic surgery. However, most lacked sufficient power to …

Study Design. This is a double blind randomized placebo controlled study, after obtaining
approval of ethics committee in the hospital and informed written consent, 64 patients were …

Total joint arthroplasty and deformity surgery of the spine can require complex reconstructive
procedures accompanied by the potential for major blood loss. In an attempt to minimize the …

BACKGROUND: Spinal reconstructive surgery in adults can be associated with significant
blood loss, often requiring allogeneic blood transfusion. The objective of this randomized …

Study Design. Systematic review. Objective. To determine the definition and incidence of
significant hemorrhage in adult spine fusion surgery, and to assess whether measures to …

Several aspects of the management of an orthopaedic surgical patient are not directly
related to the surgical technique but are nevertheless essential for a successful outcome …

Skilful surgery combined with blood-saving methods and careful management of blood
coagulation will all help reduce unnecessary blood loss and transfusion requirements …

Purpose Spine surgery is usually associated with large amount of blood loss and blood
transfusion. Excessive blood loss may cause hypotension, inadequate oxygenation of …

Postoperative haemorrhage (POH) is one of the most serious complications of any cranial
neurosurgical procedure and is associated with significant morbidity and mortality. The …