Despite being highly preventable, cervical cancer is the fourth most common cancer and
cause of cancer death in women globally. In low‐income countries, cervical cancer is often …

Vaccines are one of the most significant medical interventions in the fight against infectious
diseases. Since their discovery by Edward Jenner in 1796, vaccines have reduced the …

Background Vaccines have been demonstrated to protect against high-risk human
papillomavirus infection (HPV), including HPV-16/18, and cervical lesions among HIV …

Traditional vaccine efficacy trials usually use fixed designs with fairly large sample sizes.
Recruiting a large number of subjects requires longer time and higher costs. Furthermore …

Women living with HIV are at higher risk for human papillomavirus (HPV)-related dysplasia
and cancers and thus are prioritized for HPV vaccination. We measured HPV vaccine uptake …

HIV-infected patients are at increased risk of human papillomavirus (HPV) acquisition and
HPV-associated diseases. This study set out to determine whether a two-dose (2D) HPV …

Vaccine preventable diseases (VPDs) are a prevailing concern among the adult population,
despite availability of vaccines. Unlike pediatric vaccination programs, adult vaccination …

People living with HIV (PLH) experience higher rates of HPV infection as well as an
increased risk of HPV-related disease, including malignancies. Although they are …

Vaccine efficacy requires the production of neutralising antibodies which offer protection
against the native virus. The current gold standard for determining the presence of …

Reactogenicity events are usually the primary endpoint, in terms of safety, in vaccine clinical
trials. They are pre-specified adverse events that are commonly known to be associated with …