Immune and non-immune functions of adipose tissue leukocytes
Adipose tissue is a complex dynamic organ with whole-body immunometabolic influence.
Much of the work into understanding the role of immune cells in adipose tissue has been in …
Much of the work into understanding the role of immune cells in adipose tissue has been in …
The cell biology of fat expansion
Adipose tissue is a complex, multicellular organ that profoundly influences the function of
nearly all other organ systems through its diverse metabolite and adipokine secretome …
nearly all other organ systems through its diverse metabolite and adipokine secretome …
Pathology and pathogenesis of Chagas heart disease
KM Bonney, DJ Luthringer, SA Kim… - Annual Review of …, 2019 - annualreviews.org
Chagas heart disease is an inflammatory cardiomyopathy that develops in approximately
one-third of people infected with the protozoan parasite Trypanosoma cruzi. One way T …
one-third of people infected with the protozoan parasite Trypanosoma cruzi. One way T …
[HTML][HTML] Diagnosis and management of Chagas disease and cardiomyopathy
AL Ribeiro, MP Nunes, MM Teixeira… - Nature Reviews …, 2012 - nature.com
Chagas cardiomyopathy is the most severe and life-threatening manifestation of human
Chagas disease—a'neglected'tropical disease caused by the protozoan parasite …
Chagas disease—a'neglected'tropical disease caused by the protozoan parasite …
Bioluminescence imaging of chronic Trypanosoma cruzi infections reveals tissue‐specific parasite dynamics and heart disease in the absence of locally persistent …
Chronic T rypanosoma cruzi infections lead to cardiomyopathy in 20–30% of cases. A
causal link between cardiac infection and pathology has been difficult to establish because …
causal link between cardiac infection and pathology has been difficult to establish because …
[HTML][HTML] Current understanding of immunity to Trypanosoma cruzi infection and pathogenesis of Chagas disease
Chagas disease caused by Trypanosoma cruzi remains an important neglected tropical
disease and a cause of significant morbidity and mortality. No longer confined to endemic …
disease and a cause of significant morbidity and mortality. No longer confined to endemic …
[HTML][HTML] Navigating drug repurposing for Chagas disease: advances, challenges, and opportunities
Chagas disease is a vector-borne illness caused by the protozoan parasite Trypanosoma
cruzi (T. cruzi). It poses a significant public health burden, particularly in the poorest regions …
cruzi (T. cruzi). It poses a significant public health burden, particularly in the poorest regions …
[HTML][HTML] Chagas disease in the 21st century: a public health success or an emerging threat?
KM Bonney - Parasite, 2014 - ncbi.nlm.nih.gov
Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is a major public
health burden in Latin America and a potentially serious emerging threat to a number of …
health burden in Latin America and a potentially serious emerging threat to a number of …
[HTML][HTML] Mechanisms of cellular invasion by intracellular parasites
DM Walker, S Oghumu, G Gupta, BS McGwire… - Cellular and molecular …, 2014 - Springer
Numerous disease-causing parasites must invade host cells in order to prosper.
Collectively, such pathogens are responsible for a staggering amount of human sickness …
Collectively, such pathogens are responsible for a staggering amount of human sickness …
Ferrocene derivatives as anti-infective agents
BS Ludwig, JDG Correia, FE Kühn - Coordination Chemistry Reviews, 2019 - Elsevier
Infectious diseases like malaria, tuberculosis or HIV are among the leading causes of death
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …