Extracellular vesicles as a drug delivery system: A systematic review of preclinical studies
During the past decades, extracellular vesicles (EVs) have emerged as an attractive drug
delivery system. Here, we assess their pre-clinical applications, in the form of a systematic …
delivery system. Here, we assess their pre-clinical applications, in the form of a systematic …
Benefits of zebrafish xenograft models in cancer research
X Chen, Y Li, T Yao, R Jia - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
As a promising in vivo tool for cancer research, zebrafish have been widely applied in
various tumor studies. The zebrafish xenograft model is a low-cost, high-throughput tool for …
various tumor studies. The zebrafish xenograft model is a low-cost, high-throughput tool for …
Green metallic nanoparticles for cancer therapy: evaluation models and cancer applications
E Tinajero-Diaz, D Salado-Leza, C Gonzalez… - Pharmaceutics, 2021 - mdpi.com
Metal-based nanoparticles are widely used to deliver bioactive molecules and drugs to
improve cancer therapy. Several research works have highlighted the synthesis of gold and …
improve cancer therapy. Several research works have highlighted the synthesis of gold and …
Recent Advancement in Breast Cancer Research: Insights from Model Organisms—Mouse Models to Zebrafish
Simple Summary The current article provides an overview of the significance of using
various mouse and zebrafish models in cancer research. In addition, this review discusses …
various mouse and zebrafish models in cancer research. In addition, this review discusses …
Muscle glycogen phosphorylase and its functional partners in health and disease
M Migocka-Patrzałek, M Elias - Cells, 2021 - mdpi.com
Glycogen phosphorylase (PG) is a key enzyme taking part in the first step of glycogenolysis.
Muscle glycogen phosphorylase (PYGM) differs from other PG isoforms in expression …
Muscle glycogen phosphorylase (PYGM) differs from other PG isoforms in expression …
Three-dimensional (3D) liver cell models-a tool for bridging the gap between animal studies and clinical trials when screening liver accumulation and toxicity of …
Despite the exciting properties and wide-reaching applications of nanobiomaterials (NBMs)
in human health and medicine, their translation from bench to bedside is slow, with a …
in human health and medicine, their translation from bench to bedside is slow, with a …
[PDF][PDF] Zebrafish as An Emerging Model: An Important Testing Platform for Biomedical Science
A Dubey - Journal of Pharmaceutical Negative Results, 2022 - pnrjournal.com
This is a good thing because animals show other organisms how to stay healthy in their
environment. Biologists can learn more about a lot ofdifferent biological processes by …
environment. Biologists can learn more about a lot ofdifferent biological processes by …
Pre-clinical models of metastasis in pancreatic cancer
M Miquel, S Zhang, C Pilarsky - Frontiers in cell and developmental …, 2021 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC) is a hostile solid malignancy coupled with an
extremely high mortality rate. Metastatic disease is already found in most patients at the time …
extremely high mortality rate. Metastatic disease is already found in most patients at the time …
CD24+ CD44+ CD54+ EpCAM+ gastric cancer stem cells predict tumor progression and metastasis: clinical and experimental evidence
AA Gómez-Gallegos, L Ramírez-Vidal… - Stem Cell Research & …, 2023 - Springer
Background Gastric cancer (GC) is a leading cause of cancer-related deaths worldwide.
Specific and thorough identification of cancer cell subsets with higher tumorigenicity and …
Specific and thorough identification of cancer cell subsets with higher tumorigenicity and …
Experimental models of hepatocellular carcinoma—a preclinical perspective
A Blidisel, I Marcovici, D Coricovac, F Hut… - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is characterized by a broad molecular
and genetic heterogeneity, which makes it a challenging subject in terms of the underlying …
and genetic heterogeneity, which makes it a challenging subject in terms of the underlying …