Incongruence in the phylogenomics era
Genome-scale data and the development of novel statistical phylogenetic approaches have
greatly aided the reconstruction of a broad sketch of the tree of life and resolved many of its …
greatly aided the reconstruction of a broad sketch of the tree of life and resolved many of its …
Neural versus alternative integrative systems: molecular insights into origins of neurotransmitters
LL Moroz, DY Romanova… - … Transactions of the …, 2021 - royalsocietypublishing.org
Transmitter signalling is the universal chemical language of any nervous system, but little is
known about its early evolution. Here, we summarize data about the distribution and …
known about its early evolution. Here, we summarize data about the distribution and …
[HTML][HTML] AlphaFold predictions are valuable hypotheses and accelerate but do not replace experimental structure determination
Artificial intelligence-based protein structure prediction methods such as AlphaFold have
revolutionized structural biology. The accuracies of these predictions vary, however, and …
revolutionized structural biology. The accuracies of these predictions vary, however, and …
[HTML][HTML] Evidence for sponges as sister to all other animals from partitioned phylogenomics with mixture models and recoding
AK Redmond, A McLysaght - Nature communications, 2021 - nature.com
Resolving the relationships between the major lineages in the animal tree of life is
necessary to understand the origin and evolution of key animal traits. Sponges …
necessary to understand the origin and evolution of key animal traits. Sponges …
[HTML][HTML] Alternative neural systems: what is a neuron?(ctenophores, sponges and placozoans)
LL Moroz, DY Romanova - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
How to make a neuron, a synapse, and a neural circuit? Is there only one 'design'for a
neural architecture with a universally shared genomic blueprint across species? The brief …
neural architecture with a universally shared genomic blueprint across species? The brief …
[HTML][HTML] Osteoarthritis and toll-like receptors: when innate immunity meets chondrocyte apoptosis
G Barreto, M Manninen, K K. Eklund - Biology, 2020 - mdpi.com
Osteoarthritis (OA) has long been viewed as a degenerative disease of cartilage, but
accumulating evidence indicates that inflammation has a critical role in its pathogenesis. In …
accumulating evidence indicates that inflammation has a critical role in its pathogenesis. In …
The developmental biology of Charnia and the eumetazoan affinity of the Ediacaran rangeomorphs
Molecular timescales estimate that early animal lineages diverged tens of millions of years
before their earliest unequivocal fossil evidence. The Ediacaran macrobiota (~ 574 to 538 …
before their earliest unequivocal fossil evidence. The Ediacaran macrobiota (~ 574 to 538 …
The origin and evolution of Wnt signalling
The Wnt signal transduction pathway has essential roles in the formation of the primary body
axis during development, cellular differentiation and tissue homeostasis. This animal …
axis during development, cellular differentiation and tissue homeostasis. This animal …
A predatory gastrula leads to symbiosis-independent settlement in Aiptasia
I Maegele, S Rupp, S Özbek, A Guse… - Proceedings of the …, 2023 - National Acad Sciences
The planula larvae of the sea anemone Aiptasia have so far not been reported to complete
their life cycle by undergoing metamorphosis into adult forms. This has been a major …
their life cycle by undergoing metamorphosis into adult forms. This has been a major …
[HTML][HTML] Sensing the world and its dangers: an evolutionary perspective in neuroimmunology
Detecting danger is key to the survival and success of all species. Animal nervous and
immune systems cooperate to optimize danger detection. Preceding studies have …
immune systems cooperate to optimize danger detection. Preceding studies have …