This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily
of transporter proteins and their roles in human cells. The SLC superfamily currently …

Zinc is a ubiquitous biological metal in all living organisms. The spatiotemporal zinc
dynamics in cells provide crucial cellular signaling opportunities, but also challenges for …

Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …

Tailoring personalized cancer nanomedicines demands detailed understanding of the tumor
microenvironment. In recent years, smart upconversion nanoparticles with the ability to …

The essential trace element zinc (Zn) is widely required in cellular functions, and abnormal
Zn homeostasis causes a variety of health problems that include growth retardation …

Mammalian ATP-gated nonselective cation channels (P2XRs) can be composed of seven
possible subunits, denoted P2X1 to P2X7. Each subunit contains a large ectodomain, two …

The skin is the third most zinc (Zn)-abundant tissue in the body. The skin consists of the
epidermis, dermis, and subcutaneous tissue, and each fraction is composed of various types …

Research advances defining how zinc is transported into and out of cells and organelles
have increased exponentially within the past five years. Research has progressed through …

Two families of zinc (Zn2+) transporters are involved in zinc homeostasis in the body, SLC30
(ZnT, zinc transporter) and SLC39 (ZIP, Zinc (Zn2+)–Iron (Fe2+) Permease). The two zinc …

Zinc is an essential nutrient for all organisms because this metal serves as a catalytic or
structural cofactor for many different proteins. Zinc-dependent proteins are found in the …