Glomerular hyperfiltration in diabetes: mechanisms, clinical significance, and treatment
L Tonneijck, MHA Muskiet, MM Smits… - Journal of the …, 2017 - journals.lww.com
An absolute, supraphysiologic elevation in GFR is observed early in the natural history in
10%–67% and 6%–73% of patients with type 1 and type 2 diabetes, respectively. Moreover …
10%–67% and 6%–73% of patients with type 1 and type 2 diabetes, respectively. Moreover …
[HTML][HTML] Evaluation and management of youth-onset type 2 diabetes: a position statement by the American Diabetes Association
Although all types of diabetes result in hyperglycemia, the pathophysiology of each type of
diabetes is different. These guidelines summarize available data specific to the …
diabetes is different. These guidelines summarize available data specific to the …
Dapagliflozin in focal segmental glomerulosclerosis: a combined human-rodent pilot study
H Rajasekeran, HN Reich… - American Journal …, 2018 - journals.physiology.org
Focal segmental glomerulosclerosis (FSGS) is an important cause of nondiabetic chronic
kidney disease (CKD). Sodium-glucose cotransporter 2 inhibition (SGLT2i) therapy …
kidney disease (CKD). Sodium-glucose cotransporter 2 inhibition (SGLT2i) therapy …
Dipeptidyl Peptidase 4 Inhibition Stimulates Distal Tubular Natriuresis and Increases in Circulating SDF-1α1-67 in Patients With Type 2 Diabetes
JA Lovshin, H Rajasekeran, Y Lytvyn… - Diabetes …, 2017 - Am Diabetes Assoc
OBJECTIVE Antihyperglycemic agents, such as empagliflozin, stimulate proximal tubular
natriuresis and improve cardiovascular and renal outcomes in patients with type 2 diabetes …
natriuresis and improve cardiovascular and renal outcomes in patients with type 2 diabetes …
[HTML][HTML] Eucommia ulmoides (Tochu) and its extract geniposidic acid reduced blood pressure and improved renal hemodynamics
A Ishimitsu, A Tojo, H Satonaka, T Ishimitsu - Biomedicine & …, 2021 - Elsevier
Introduction Eucommia ulmoides leaves are used as Tochu tea, which has a blood pressure
lowering effect of unknown mechanism. Purpose and Methods The effects of Tochu tea and …
lowering effect of unknown mechanism. Purpose and Methods The effects of Tochu tea and …
Renal hemodynamic effects differ between antidiabetic combination strategies: randomized controlled clinical trial comparing empagliflozin/linagliptin with metformin …
C Ott, S Jung, M Korn, D Kannenkeril, A Bosch… - Cardiovascular …, 2021 - Springer
Background Type 2 diabetes causes cardio-renal complications and is treated with different
combination therapies. The renal hemodynamics profile of such combination therapies has …
combination therapies. The renal hemodynamics profile of such combination therapies has …
Minireview: Understanding and targeting inflammatory, hemodynamic and injury markers for cardiorenal protection in type 1 diabetes
L Kugathasan, VS Sridhar, KL Tommerdahl, C Xu… - Metabolism, 2024 - Elsevier
The coexistence of cardiovascular disease (CVD) and diabetic kidney disease (DKD) is
common in people with type 1 diabetes (T1D) and is strongly associated with an increased …
common in people with type 1 diabetes (T1D) and is strongly associated with an increased …
Pima Indian contributions to our understanding of diabetic kidney disease
Prospective studies in informative populations are crucial to increasing our knowledge of
disease. In this perspective, we describe a half century of studies in an American Indian …
disease. In this perspective, we describe a half century of studies in an American Indian …
Perspectives on the role of magnetic resonance imaging (MRI) for noninvasive evaluation of diabetic kidney disease
JM Mora-Gutiérrez, MA Fernández-Seara… - Journal of Clinical …, 2021 - mdpi.com
Renal magnetic resonance imaging (MRI) techniques are currently in vogue, as they provide
in vivo information on renal volume, function, metabolism, perfusion, oxygenation, and …
in vivo information on renal volume, function, metabolism, perfusion, oxygenation, and …
Renal hyperfiltration in adolescents with type 2 diabetes: physiology, sex differences, and implications for diabetic kidney disease
P Bjornstad, DZ Cherney - Current diabetes reports, 2018 - Springer
Abstract Purpose of Review Compared to adult-onset type 2 diabetes (T2D), youth with T2D
have a more aggressive phenotype with greater insulin resistance (IR), more rapid β cell …
have a more aggressive phenotype with greater insulin resistance (IR), more rapid β cell …