[HTML][HTML] Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders
Oligodendrocyte precursor cells (OPCs) account for 5% of the resident parenchymal central
nervous system glial cells. OPCs are not only a back-up for the loss of oligodendrocytes that …
nervous system glial cells. OPCs are not only a back-up for the loss of oligodendrocytes that …
[HTML][HTML] Thyroid hormones interaction with immune response, inflammation and non-thyroidal illness syndrome
The interdependence between thyroid hormones (THs), namely, thyroxine and
triiodothyronine, and immune system is nowadays well-recognized, although not yet fully …
triiodothyronine, and immune system is nowadays well-recognized, although not yet fully …
[HTML][HTML] Chemical mechanisms of nanoparticle radiosensitization and radioprotection: a review of structure-function relationships influencing reactive oxygen species
Metal nanoparticles are of increasing interest with respect to radiosensitization. The physical
mechanisms of dose enhancement from X-rays interacting with nanoparticles has been well …
mechanisms of dose enhancement from X-rays interacting with nanoparticles has been well …
[HTML][HTML] MicroRNAs in the regulation of cellular redox status and its implications in myocardial ischemia-reperfusion injury
T Carbonell, AV Gomes - Redox biology, 2020 - Elsevier
MicroRNAs (miRNAs) are small RNAs that do not encode for proteins and play key roles in
the regulation of gene expression. miRNAs are involved in a comprehensive range of …
the regulation of gene expression. miRNAs are involved in a comprehensive range of …
ROS as regulators of cellular processes in melanoma
In this review, we examine the multiple roles of ROS in the pathogenesis of melanoma,
focusing on signal transduction and regulation of gene expression. In recent years, different …
focusing on signal transduction and regulation of gene expression. In recent years, different …
Molecular and cellular basis of the anticancer activity of the prenylated flavonoid icaritin in hepatocellular carcinoma
C Bailly - Chemico-biological interactions, 2020 - Elsevier
The prenylated flavonoid icaritin (ICT) is currently undergoing phase 3 clinical trial for the
treatment of advanced hepatocellular carcinoma (HCC), based on a solid array of preclinical …
treatment of advanced hepatocellular carcinoma (HCC), based on a solid array of preclinical …
[HTML][HTML] Oxidative stress and microRNAs in endothelial cells under metabolic disorders
Reactive oxygen species (ROS) are radical oxygen intermediates that serve as important
second messengers in signal transduction. However, when the accumulation of these …
second messengers in signal transduction. However, when the accumulation of these …
[HTML][HTML] Integrated molecular signaling involving mitochondrial dysfunction and alteration of cell metabolism induced by tyrosine kinase inhibitors in cancer
MA Rodríguez-Hernández, P de la Cruz-Ojeda… - Redox Biology, 2020 - Elsevier
Cancer cells have unlimited replicative potential, insensitivity to growth-inhibitory signals,
evasion of apoptosis, cellular stress, and sustained angiogenesis, invasiveness and …
evasion of apoptosis, cellular stress, and sustained angiogenesis, invasiveness and …
[HTML][HTML] Anti-angiogenic effects of phytochemicals on miRNA regulating breast cancer progression
Several phytochemicals have been identified for their role in modifying miRNA regulating
tumor progression. miRNAs modulate the expression of several oncogenes and tumor …
tumor progression. miRNAs modulate the expression of several oncogenes and tumor …
Metastasis prevention: How to catch metastatic seeds
TS Gerashchenko, AA Schegoleva… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Despite considerable advances in the evolution of anticancer therapies, metastasis still
remains the main cause of cancer mortality. Therefore, current strategies for cancer cure …
remains the main cause of cancer mortality. Therefore, current strategies for cancer cure …