Renal control of calcium, phosphate, and magnesium homeostasis

J Blaine, M Chonchol, M Levi - … Journal of the American Society of …, 2015 - journals.lww.com
Calcium, phosphate, and magnesium are multivalent cations that are important for many
biologic and cellular functions. The kidneys play a central role in the homeostasis of these …

Manganese is essential for neuronal health

KJ Horning, SW Caito, KG Tipps… - Annual review of …, 2015 - annualreviews.org
The understanding of manganese (Mn) biology, in particular its cellular regulation and role
in neurological disease, is an area of expanding interest. Mn is an essential micronutrient …

Multifunctions of dual Zn/Mg ion co-implanted titanium on osteogenesis, angiogenesis and bacteria inhibition for dental implants

Y Yu, G Jin, Y Xue, D Wang, X Liu, J Sun - Acta biomaterialia, 2017 - Elsevier
In order to improve the osseointegration and long-term survival of dental implants, it is
urgent to develop a multifunctional titanium surface which would simultaneously have …

Cellular magnesium homeostasis

AMP Romani - Archives of biochemistry and biophysics, 2011 - Elsevier
Magnesium, the second most abundant cellular cation after potassium, is essential to
regulate numerous cellular functions and enzymes, including ion channels, metabolic …

Second messenger role for Mg2+ revealed by human T-cell immunodeficiency

FY Li, B Chaigne-Delalande, C Kanellopoulou… - Nature, 2011 - nature.com
Abstract The magnesium ion, Mg2+, is essential for all life as a cofactor for ATP,
polyphosphates such as DNA and RNA, and metabolic enzymes, but whether it plays a part …

[HTML][HTML] Mitochondrial channels: ion fluxes and more

I Szabo, M Zoratti - Physiological reviews, 2014 - journals.physiology.org
The field of mitochondrial ion channels has recently seen substantial progress, including the
molecular identification of some of the channels. An integrative approach using genetics …

[HTML][HTML] Magnesium is a key player in neuronal maturation and neuropathology

R Yamanaka, Y Shindo, K Oka - International journal of molecular …, 2019 - mdpi.com
Magnesium (Mg) is the second most abundant cation in mammalian cells, and it is essential
for numerous cellular processes including enzymatic reactions, ion channel functions …

Mg2+ Regulates Cytotoxic Functions of NK and CD8 T Cells in Chronic EBV Infection Through NKG2D

B Chaigne-Delalande, FY Li, GM O'Connor, MJ Lukacs… - Science, 2013 - science.org
The magnesium transporter 1 (MAGT1) is a critical regulator of basal intracellular free
magnesium (Mg2+) concentrations. Individuals with genetic deficiencies in MAGT1 have …

[HTML][HTML] MLKL forms cation channels

B Xia, S Fang, X Chen, H Hu, P Chen, H Wang, Z Gao - Cell research, 2016 - nature.com
The mixed lineage kinase domain-like (MLKL) protein is a key factor in tumor necrosis factor-
induced necroptosis. Recent studies on necroptosis execution revealed a commitment role …

[HTML][HTML] TRPM7 is essential for Mg2+ homeostasis in mammals

LV Ryazanova, LJ Rondon, S Zierler, Z Hu… - Nature …, 2010 - nature.com
Mg2+ is the second-most abundant cation in animal cells and is an essential cofactor in
numerous enzymatic reactions. The molecular mechanisms controlling Mg2+ balance in the …