Ice inhibition for cryopreservation: materials, strategies, and challenges

T Chang, G Zhao - Advanced Science, 2021 - Wiley Online Library
Cryopreservation technology has developed into a fundamental and important supporting
method for biomedical applications such as cell‐based therapeutics, tissue engineering …

[HTML][HTML] Regulating ice formation for enhancing frozen food quality: Materials, mechanisms and challenges

L Sun, Z Zhu, DW Sun - Trends in Food Science & Technology, 2023 - Elsevier
Background Freezing reduces the temperature of the food system and extends the shelf life
of food. However, the inevitable formation of ice crystals could impact food quality. Small …

A general crosslinker strategy to realize intrinsic frozen resistance of hydrogels

D Zhang, Y Liu, Y Liu, Y Peng, Y Tang… - Advanced …, 2021 - Wiley Online Library
Abstract Development and understanding of antifreezing materials are fundamentally and
practically important for materials design and delivery. However, almost all of antifreezing …

Design principles of microneedles for drug delivery and sampling applications

Z Le, J Yu, YJ Quek, B Bai, X Li, Y Shou, B Myint, C Xu… - Materials Today, 2023 - Elsevier
Microneedles technology is a powerful platform to achieve efficient transdermal delivery of
bioactive molecules for local or systemic therapies attributing to their minimally invasive …

Bioinspired ice-binding materials for tissue and organ cryopreservation

Z Liu, X Zheng, J Wang - Journal of the American Chemical …, 2022 - ACS Publications
Cryopreservation of tissues and organs can bring transformative changes to medicine and
medical science. In the past decades, limited progress has been achieved, although …

The atomistic details of the ice recrystallisation inhibition activity of PVA

F Bachtiger, TR Congdon, C Stubbs, MI Gibson… - Nature …, 2021 - nature.com
Understanding the ice recrystallisation inhibition (IRI) activity of antifreeze biomimetics is
crucial to the development of the next generation of cryoprotectants. In this work, we bring …

Nanoscopy of single antifreeze proteins reveals that reversible ice binding is sufficient for ice recrystallization inhibition but not thermal hysteresis

RP Tas, MMRM Hendrix… - Proceedings of the …, 2023 - National Acad Sciences
Antifreeze proteins (AFPs) bind ice to reduce freezing temperatures and arrest ice crystal
ripening, making AFPs essential for the survival of many organisms in ice-laden …

Control strategies of ice nucleation, growth, and recrystallization for cryopreservation

M Lin, H Cao, J Li - Acta Biomaterialia, 2023 - Elsevier
The cryopreservation of biomaterials is fundamental to modern biotechnology and
biomedicine, but the biggest challenge is the formation of ice, resulting in fatal cryoinjury to …

Inhibition of ice recrystallization by tamarind (Tamarindus indica L.) seed polysaccharide and molecular weight effects

X Sun, R Guo, Y Kou, H Song, T Zhan, J Wu… - Carbohydrate …, 2023 - Elsevier
This study aimed to investigate the inhibition effects of tamarind seed polysaccharide (TSP)
on ice recrystallization and to figure out its possible molecular weight-dependent effects …

A review of natural polysaccharides for food cryoprotection: Ice crystals inhibition and cryo-stabilization

X Sun, Y Wu, Z Song, X Chen - Bioactive Carbohydrates and Dietary Fibre, 2022 - Elsevier
Although freezing is by far the most common method of food preservation, deteriorative
changes in food quality are inevitable because of the formation of ice crystals and other …