Atherosclerosis, as a chronic inflammatory response, is one of the main causes of
cardiovascular diseases. Atherosclerosis is induced by endothelial cell dysfunction …

Abstract Background Cardiovascular diseases (CVDs) are among the deadliest non-
communicable diseases, and millions of dollars are spent every year to combat CVDs …

Diabetes-related vascular complications include diabetic cardiovascular diseases (CVD),
diabetic nephropathy (DN) and diabetic retinopathy, etc. DN can promote the process of end …

Abstract Purpose of Review The purpose of this review is to summarize the most recent
findings investigating the impact of several natural sirtuin (SIRT) activators, particularly …

The Kelch-like ECH associated protein 1 (Keap1)/nuclear factor erythroid 2-related factor 2
(Nrf2)/antioxidant response elements (ARE) signaling pathway is considered a master …

The immune response encompasses innate and adaptive immunity, each with distinct and
specific activities. The innate immune system is constituted by phagocytic cells …

Objectives The activation of mast cell (MC) plays an important part in the pathogenesis of
chronic urticaria (CU), and the expression of MRGPRX2 (Mas-related G-protein coupled …

Systemic inflammation includes a widespread immune response to a harmful stimulus that
results in extensive systemic damage. One common example of systemic inflammation is …

The incidence and mortality rate of atherosclerotic cardiovascular disease (ASCVD) is
increasing yearly worldwide. Recently, a growing body of evidence has unveiled the anti …

Chemokines, also known as chemotactic cytokines, stimulate the migration of immune cells.
These molecules play a key role in the pathogenesis of inflammation leading to …