An overview of gene regulation in bacteria by small RNAs derived from mRNA 3′ ends
Over the past two decades, small noncoding RNAs (sRNAs) that regulate mRNAs by short
base pairing have gone from a curiosity to a major class of post-transcriptional regulators in …
base pairing have gone from a curiosity to a major class of post-transcriptional regulators in …
Specific and Global RNA Regulators in Pseudomonas aeruginosa
P Pusic, E Sonnleitner, U Bläsi - International Journal of Molecular …, 2021 - mdpi.com
Pseudomonas aeruginosa (Pae) is an opportunistic pathogen showing a high intrinsic
resistance to a wide variety of antibiotics. It causes nosocomial infections that are particularly …
resistance to a wide variety of antibiotics. It causes nosocomial infections that are particularly …
Phage proteins target and co-opt host ribosomes immediately upon infection
M Gerovac, K Chihara, L Wicke, B Böttcher… - Nature …, 2024 - nature.com
Bacteriophages must seize control of the host gene expression machinery to replicate. To
bypass bacterial anti-phage defence systems, this host takeover occurs immediately upon …
bypass bacterial anti-phage defence systems, this host takeover occurs immediately upon …
Integrated Omics Reveal Time-Resolved Insights into T4 Phage Infection of E. coli on Proteome and Transcriptome Levels
M Wolfram-Schauerte, N Pozhydaieva, M Viering… - Viruses, 2022 - mdpi.com
Bacteriophages are highly abundant viruses of bacteria. The major role of phages in
shaping bacterial communities and their emerging medical potential as antibacterial agents …
shaping bacterial communities and their emerging medical potential as antibacterial agents …
Grad-seq identifies KhpB as a global RNA-binding protein in Clostridioides difficile that regulates toxin production
V Lamm-Schmidt, M Fuchs, J Sulzer, M Gerovac… - …, 2021 - academic.oup.com
Much of our current knowledge about cellular RNA–protein complexes in bacteria is derived
from analyses in gram-negative model organisms, with the discovery of RNA-binding …
from analyses in gram-negative model organisms, with the discovery of RNA-binding …
Global profiling of the RNA and protein complexes of Escherichia coli by size exclusion chromatography followed by RNA sequencing and mass spectrometry (SEC …
New methods for the global identification of RNA–protein interactions have led to greater
recognition of the abundance and importance of RNA-binding proteins (RBPs) in bacteria …
recognition of the abundance and importance of RNA-binding proteins (RBPs) in bacteria …
[HTML][HTML] Exploring the transcriptional landscape of phage–host interactions using novel high-throughput approaches
L Putzeys, L Wicke, A Brandão, M Boon… - Current Opinion in …, 2024 - Elsevier
In the last decade, powerful high-throughput sequencing approaches have emerged to
analyse microbial transcriptomes at a global scale. However, to date, applications of these …
analyse microbial transcriptomes at a global scale. However, to date, applications of these …
The intricate organizational strategy of nucleus-forming phages
A Prichard, J Pogliano - Current Opinion in Microbiology, 2024 - Elsevier
Nucleus-forming phages (chimalliviruses) encode numerous genes responsible for creating
intricate structures for viral replication. Research on this newly appreciated family of phages …
intricate structures for viral replication. Research on this newly appreciated family of phages …
The world of stable ribonucleoproteins and its mapping with Grad-seq and related approaches
Macromolecular complexes of proteins and RNAs are essential building blocks of cells.
These stable supramolecular particles can be viewed as minimal biochemical units whose …
These stable supramolecular particles can be viewed as minimal biochemical units whose …
In vivo targets of Salmonella FinO include a FinP-like small RNA controlling copy number of a cohabitating plasmid
Y El Mouali, M Gerovac, R Mineikaitė… - Nucleic acids …, 2021 - academic.oup.com
FinO-domain proteins represent an emerging family of RNA-binding proteins (RBPs) with
diverse roles in bacterial post-transcriptional control and physiology. They exhibit an …
diverse roles in bacterial post-transcriptional control and physiology. They exhibit an …