Background A major driver of antimicrobial resistance (AMR) and poor clinical outcomes is
suboptimal antibiotic use, although data are lacking in low-resource settings. We reviewed …

Purpose Sepsis is a common complication in patients with cancer, but studies evaluating the
outcomes of critically ill cancer patients with sepsis on a global scale are limited. We aimed …

Objectives To compare the accuracy of the Sequential Organ Failure Assessment (SOFA)
and Acute Physiology and Chronic Health Evaluation II (APACHE II) Scores in predicting …

Background The simple scoring systems for predicting the outcome of sepsis in intensive
care units (ICUs) are few, especially for limited-resource settings. Therefore, this study …

Purpose Colistin's FDA weight-based dosing (WBD) and frequency are both expressed in a
broad range. Therefore, a simplified fixed-dose regimen (SFDR) of intravenous colistin …

RESUMO A sepse pode provocar falência de órgãos e choques quando não tratada de
forma precoce e adequada, portanto caracteriza-se como uma condição de grande risco à …

Sepsis still becomes a major health problem worldwide, with a fairly high mortality rate
ranging from 20 to 50%. Antibiotic therapy with rational use can reduce the mortality rate. In …

Background Antimicrobial resistance (AMR) is one of the leading global public health threats
of the 21st Century. Antimicrobial stewardship (AMS) programmes have been shown to …

Background: Drug Utilization Evaluation (DUE) studies are designed to assess drug usage
appropriateness. This study aimed to evaluate the drug utilization of antibiotics in the …

Sepsis is a syndrome initiated by an infection in which an aberrant host response to the
initiating microbe leads to organ dysfunction, and, all too frequently, mortality. An enormous …