The maintenance of immunological tolerance of B lymphocytes is a complex and critical
process that must be implemented as to avoid the detrimental development of autoreactivity …

Type 1 diabetes mellitus (T1DM) is a long‐term and chronic autoimmune disorder, in which
the immune system attacks the pancreatic β‐cells. Both adaptive and innate immune …

Chemokines and their receptors have been associated with or implicated in the
pathogenesis of type 1 diabetes (T1D), but the identification of a single specific …

Though type 1 diabetes (T1D) is considered a T cell-mediated autoimmune disorder, recent
evidence indicates that B cells play a critical role in disease. This conclusion is based in part …

Intermediate filaments are the most heterogeneous class among cytoskeletal elements.
While some of them have been well-characterized, little is known about peripherin …

Abstract α-Internexin and peripherin are neuronal-specific intermediate filament (IF)
proteins. α-Internexin is a type IV IF protein like the neurofilament triplet proteins (NFTPs …

Inflammation is known to be involved in the progression of diabetic retinopathy. Follicular
helper T cells (Tfh) play critical roles in the differentiation of long-live plasma cells and …

Type 2 diabetes mellitus (T2 DM) is characterized by a chronic low‐grade inflammatory
state. Follicular helper T cells (Tfh) play critical roles in inducing B‐cell activation and …

Corynebacterium pseudotuberculosis (C. pseudotuberculosis) is a zoonotic pathogen that
can cause cheese lymphadenitis in goats. In order to obtain detailed information about the …

A major goal in understanding autoimmune diseases is to define the antigens that elicit a
self-destructive immune response, but this is a difficult endeavor. In an effort to discover …