The protein menin is encoded by the MEN1 gene, which is mutated in patients with multiple
endocrine neoplasia type 1 (MEN1) syndrome. Although menin acts as a tumor suppressor …

Simple Summary Pancreatic neuroendocrine tumors (pNETs) are rare, indolent cancers
whose causation is only partly understood. An increasing number of studies have uncovered …

Menin is a tumour suppressor protein whose loss or inactivation causes multiple endocrine
neoplasia 1 (MEN1), a hereditary autosomal dominant tumour syndrome that is …

The majority of parathyroid disease encountered in routine practice is due to single
parathyroid adenoma, of which the majority arise as sporadic tumors. This is usually a …

The Wnt signaling pathway plays crucial roles during embryonic development, whose
aberration is implicated in a variety of human cancers. Axin, a key component of canonical …

Although anatomic imaging to assess the precise localization of pheochromocytomas/
paragangliomas (PHEOs/PGLs) is unavoidable before any surgical intervention on these …

Menin, which is encoded by the multiple endocrine neoplasia type 1 (MEN1) gene, is a
tumor suppressor and transcriptional regulator. Menin controls proliferation and apoptosis of …

Since the discovery of the multiple endocrine neoplasia type 1 (MEN1) gene in 1997,
elucidation of the molecular function of its protein product, menin, has been a challenge …

There is a trend of increasing prevalence of neuroendocrine tumors (NETs), and the
inherited multiple endocrine neoplasia type 1 (MEN1) syndrome serves as a genetic model …

Background: A gastric cancer (GC) diagnosis relies on histopathology. Endoscopy rates are
increasing. Helicobacter pylori infection is a major GC risk factor. In an effort to elucidate …