The proper functioning of the pathways that are involved in the sensing and management of
nutrients is central to metabolic homeostasis and is therefore among the most fundamental …

Dysfunctional visceral fat plays a key role in the initiation and maintenance of chronic
inflammation, liver steatosis and subsequent systemic insulin resistance that primes the …

Macrophages show endoplasmic reticulum (ER) stress when exposed to lipotoxic signals
associated with atherosclerosis, although the pathophysiological importance and the …

Objective A novel approach to regulate obesity-associated adipose inflammation may be
through metabolic reprogramming of macrophages (MΦs). Broadly speaking, MΦs …

Objective The adipocyte/macrophage fatty acid-binding protein 4 (FABP4) has been
described as a biomarker for adiposity and metabolic syndrome (MS). The aims of this study …

A mismatch between fetal and postnatal environment can permanently alter the body
structure and physiology and therefore contribute later to obesity and related disorders, as …

Objective Chemerin, a recently identified adipokine, has been linked to adiposity, insulin
resistance, metabolic syndrome risk factors and inflammation. Here, we evaluated whether a …

Intramuscular fat (IMF) content is an important determinant of quality characteristics such as
tenderness, juiciness and flavour, and of its acceptability by consumers. Research has …

Diabetes is a disease that affects over 150 million people worldwide for which there are
multiple oral and injectable medications. Because of trends in obesity and sedentary …

Activation of proinflammatory macrophages plays an important role in the pathogenesis of
insulin resistance, type 2 diabetes, and atherosclerosis. Previous work using high fat-fed …