Diagnostic, prognostic, and therapeutic significance of long non-coding RNA MALAT1 in cancer
Abstract Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1) is a widely
studied lncRNA in cancer. Although dispensable for normal physiology, MALAT1 is …
studied lncRNA in cancer. Although dispensable for normal physiology, MALAT1 is …
[HTML][HTML] MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches
The deeper understanding of non-coding RNAs has recently changed the dogma of
molecular biology assuming protein-coding genes as unique functional biological effectors …
molecular biology assuming protein-coding genes as unique functional biological effectors …
[HTML][HTML] m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade
Melanoma is one of the most deadly and therapy-resistant cancers. Here we show that N6-
methyladenosine (m6A) mRNA demethylation by fat mass and obesity-associated protein …
methyladenosine (m6A) mRNA demethylation by fat mass and obesity-associated protein …
MALAT1: a potential biomarker in cancer
ZX Li, QN Zhu, HB Zhang, Y Hu, G Wang… - Cancer management …, 2018 - Taylor & Francis
Purpose The research of long non-coding RNAs (lncRNAs) has become a new passion with
the discovery of abundant new lncRNAs and extensive investigation of their roles in various …
the discovery of abundant new lncRNAs and extensive investigation of their roles in various …
[HTML][HTML] Role and therapeutic targeting of the PI3K/Akt/mTOR signaling pathway in skin cancer: a review of current status and future trends on natural and synthetic …
The mammalian or mechanistic target of rapamycin (mTOR) and associated phosphatidyl-
inositiol 3-kinase (PI3K)/protein kinase B (Akt) pathways regulate cell growth, differentiation …
inositiol 3-kinase (PI3K)/protein kinase B (Akt) pathways regulate cell growth, differentiation …
Long non-coding RNAs (lncRNAs); roles in tumorigenesis and potentials as biomarkers in cancer diagnosis
S Najafi, SH Khatami, M Khorsand, Z Jamali… - Experimental cell …, 2022 - Elsevier
New research has indicated that long non-coding RNAs (lncRNAs) play critical roles in a
broad range of biological processes, including the pathogenesis of many complex human …
broad range of biological processes, including the pathogenesis of many complex human …
Long non-coding RNA MALAT1 promotes proliferation and invasion via targeting miR-129-5p in triple-negative breast cancer
Y Zuo, Y Li, Z Zhou, M Ma, K Fu - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Background Long non-coding RNA Metastasis associated lung adenocarcinoma transcript 1
(lncRNA MALAT1) play important roles in tumor progression. In the present study, we …
(lncRNA MALAT1) play important roles in tumor progression. In the present study, we …
[HTML][HTML] LncRNA SNHG3/miRNA-151a-3p/RAB22A axis regulates invasion and migration of osteosarcoma
S Zheng, F Jiang, D Ge, J Tang, H Chen, J Yang… - Biomedicine & …, 2019 - Elsevier
To elucidate the potential function of lncRNA SNHG3 in the development of osteosarcoma.
Quantitative real-time polymerase chain reaction was conducted for detection of SNHG3 …
Quantitative real-time polymerase chain reaction was conducted for detection of SNHG3 …
[HTML][HTML] The role of non-coding RNAs in controlling cell cycle related proteins in cancer cells
Cell cycle is regulated by a number of proteins namely cyclin-dependent kinases (CDKs)
and their associated cyclins which bind with and activate CDKs in a phase specific manner …
and their associated cyclins which bind with and activate CDKs in a phase specific manner …
LncRNA TUG1 influences papillary thyroid cancer cell proliferation, migration and EMT formation through targeting miR-145
H Lei, Y Gao, X Xu - Acta biochimica et biophysica Sinica, 2017 - academic.oup.com
LncRNA TUG1, a tumor oncogene associated with various human cancers, has been
reported to be involved in regulating various cellular processes, such as proliferation …
reported to be involved in regulating various cellular processes, such as proliferation …