In 1996, when Dolly the sheep was born, a new, utopian era was expected to begin. Science
fiction and popular culture instantly threatened the public with shortly upcoming human …

Mammalian oocytes can reprogram differentiated somatic cells into a totipotent state through
somatic cell nuclear transfer (SCNT), which is known as cloning. Although many mammalian …

The basic units of chromatin are nucleosomes, that are made up of DNA wrapped around
histone cores. Histone lysine residue is a common location for posttranslational …

The cloning between different animals known as interspecific somatic cell nuclear transfer
(iSCNT) was carried out for endangered species. The iSCNT has been characterized by a …

Embryo production through somatic cell nuclear transfer (SCNT) is a powerful tool to
produce elite sheep and preserve endangered wild species. However, the rate of newborns …

Simple Summary Different reproductive biotechnologies have been applied to sheep, such
as cloning, which has been successfully applied in this species. In this context, the aim of the …

Context Incomplete epigenetic reprogramming of histone deacetylation (HDAC) is one of the
main reasons for the low efficiency of somatic cell nuclear transfer (SCNT). Scriptaid is a …

Embryo production in donkeys is inefficient compared with that in other livestock. Obtaining
a sufficient number of MII oocytes is the first step to solving this problem. In this study, the …

Simple Summary Interspecies SCNT-based cloning and in vitro production of interspecies
SCNT-derived embryos allows cells that have undergone terminal differentiation to be …

Somatic cell nuclear transfer (SCNT) is a reproductive biotechnology with great potential in
the reproduction of different species of zootechnical interest, including sheep. This study …