Abstract The thiazide-sensitive Na+–Cl− cotransporter (TSC) is responsible for the major
sodium chloride reabsorption pathway, which is located in the apical membrane of the …

Background and objective: Incidences of hypertension are increasing and this condition is
more common in men than in women. We selected six well-characterized polymorphisms …

Background. Few studies have examined gene expression in peripheral blood mononuclear
cells (PBMCs) after a dietary intervention. Objective. Our study is aimed at evaluating in a …

Background and Objective Via direct sequencing, we have recently identified six common
polymorphisms in angiotensin receptor-like 1 (AGTRL1) gene, and found only two …

Abstract Serine/threonine kinase 39 (STK39) gene has been reported to be a hypertension-
susceptibility gene by a recent genome-wide association study in Western populations. To …

PURPOSE: Obesogenic environments in children, in particular excessive intake of sodium,
generate hypertension, which is a major risk factor for chronic diseases. METHODS: In all …

In this study, we sought to examine the association between 10 genetic variants in the matrix
metalloproteinase (MMP) family genes and the risk of hypertension among northeastern …

1. NCC 基因表达与低血压: Schultheis 等[19] 运用基因打靶技术敲除小鼠的NCC 调控基因,
给予野生鼠和实验鼠低钠饮食, 两周后发现实验组小鼠的血压明显低于野生小鼠的血压 …

The aim of this study was to examine the individual and interactive associations of five non-
synonymous variants of four DNA repair relevant genes (XRCC1, XRCC3, hOGG1, NQO1) …

Mounting evidence has implicated the SLC12A3 gene in essential hypertension. Here, we
examined the potential associations of common variants of the SLC12A3 gene with blood …