Numerous studies have shown that oxidative stress resulting from an imbalance between
the production of free radicals and their neutralization by antioxidant enzymes is one of the …

This systematic review extensively investigated the role of the genetic and transcriptomic
factors in late complications of type 2 diabetes mellitus (T2DM) and the current approaches …

Background Nowadays little is known about the molecular profile of the occluding thrombus
of patients with ischemic stroke. Objectives To analyze the proteomic profile of thrombi in …

The aim of this pilot study was to investigate whether single nucleotide polymorphisms
(SNP) in the gene encoding the catalytic subunit of glutamate cysteine ligase (GCLC) are …

The SERBP1 gene is a well-known regulator of SERPINE1 mRNA stability and
progesterone signaling. However, the chaperone-like properties of SERBP1 have recently …

HSPA8 is involved in many stroke-associated cellular processes, playing a pivotal role in the
protein quality control system. Here we report the results of the pilot study aimed at …

Since SLCO1B1 encodes the uptake transporter OATP1B1, which can influence the
pharmacokinetic and pharmacodynamic profiles of edoxaban, polymorphisms in SLCO1B1 …

Background: Ischemic stroke (IS) is the leading cause of death and disability worldwide.
Chaperone proteins protect brain cells from the ischemic damage by restoring the structures …

The aim of this pilot study was to investigate whether polymorphisms in the gene encoding
heat shock factor 1 (HSF1), a transcriptional activator of molecular chaperones, play a role in …

Objectives Increased plasma gamma-glutamyl transferase (GGT1) has been identified as a
robust and independent risk factor for ischemic stroke (IS), but the molecular mechanisms of …