Cyclic decidualization of the human endometrium in reproductive health and failure

B Gellersen, JJ Brosens - Endocrine reviews, 2014 - academic.oup.com
Decidualization denotes the transformation of endometrial stromal fibroblasts into
specialized secretory decidual cells that provide a nutritive and immunoprivileged matrix …

CD45 in human physiology and clinical medicine

A Rheinländer, B Schraven, U Bommhardt - Immunology letters, 2018 - Elsevier
CD45 is an evolutionary highly conserved receptor protein tyrosine phosphatase exclusively
expressed on all nucleated cells of the hematopoietic system. It is characterized by the …

Epiblast inducers capture mouse trophectoderm stem cells in vitro and pattern blastoids for implantation in utero

J Seong, J Frias-Aldeguer, V Holzmann, H Kagawa… - Cell stem cell, 2022 - cell.com
The embryo instructs the allocation of cell states to spatially regulate functions. In the
blastocyst, patterning of trophoblast (TR) cells ensures successful implantation and …

[HTML][HTML] Single-cell transcriptome profiling of the human endometrium of patients with recurrent implantation failure

ZZ Lai, Y Wang, WJ Zhou, Z Liang, JW Shi, HL Yang… - Theranostics, 2022 - ncbi.nlm.nih.gov
Introduction: Despite great advances in assisted reproductive technology (ART), recurrent
implantation failure (RIF) cannot be effectively avoided. Notably, cellular characteristics and …

Galectin-1: a traditionally immunosuppressive protein displays context-dependent capacities

X Yu, J Qian, L Ding, S Yin, L Zhou… - International Journal of …, 2023 - mdpi.com
Galectin–Carbohydrate interactions are indispensable to pathogen recognition and immune
response. Galectin-1, a ubiquitously expressed 14-kDa protein with an evolutionarily …

[HTML][HTML] T cell behavior at the maternal-fetal interface

P Nancy, A Erlebacher - The International journal of developmental …, 2014 - ncbi.nlm.nih.gov
Understanding the function of T cells at the maternal-fetal interface remains one of the most
difficult problems in reproductive immunology. A great deal of work over the last two …

Gut and reproductive tract microbiota adaptation during pregnancy: new insights for pregnancy-related complications and therapy

M De Siena, L Laterza, MV Matteo, I Mignini, T Schepis… - Microorganisms, 2021 - mdpi.com
Pregnancy is characterized by maternal adaptations that are necessary to create a
welcoming and hospitable environment for the fetus. Studies have highlighted how the …

CircRNA fibroblast growth factor receptor 3 promotes tumor progression in non‐small cell lung cancer by regulating Galectin‐1‐AKT/ERK1/2 signaling

BQ Qiu, PF Zhang, D Xiong, JJ Xu… - Journal of cellular …, 2019 - Wiley Online Library
The dysregulation of circular RNA (circRNA) expression is involved in the progression of
several cancers, including non‐small cell lung cancer (NSCLC). However, the role and …

Immunology of the Placenta

M Tong, VM Abrahams - Obstetrics and Gynecology Clinics, 2020 - obgyn.theclinics.com
Pregnancy is an immune paradox in which the mother must tolerate the fetus, a
semiallograft, while at the same time maintain immune defense against pathogens. From the …

Galectin-1 attenuates neurodegeneration in Parkinson's disease model by modulating microglial MAPK/IκB/NFκB axis through its carbohydrate-recognition domain

Y Li, N Chen, C Wu, Y Lu, G Gao, C Duan… - Brain, Behavior, and …, 2020 - Elsevier
The vicious cycle between the chronic activation of microglia and dopamine neurons
degeneration is linked with the progression of Parkinson's disease (PD). Targeting …