Perspectives on the treatment of malignant pleural mesothelioma
Mesothelioma Most mesotheliomas originate in the pleura and are due to asbestos
exposure. The incidence is decreasing somewhat with asbestos remediation, but mortality …
exposure. The incidence is decreasing somewhat with asbestos remediation, but mortality …
Inhibition of FGF‐FGFR and VEGF‐VEGFR signalling in cancer treatment
G Liu, T Chen, Z Ding, Y Wang, Y Wei, X Wei - Cell proliferation, 2021 - Wiley Online Library
The sites of targeted therapy are limited and need to be expanded. The FGF‐FGFR
signalling plays pivotal roles in the oncogenic process, and FGF/FGFR inhibitors are a …
signalling plays pivotal roles in the oncogenic process, and FGF/FGFR inhibitors are a …
[HTML][HTML] Malignant pleural mesothelioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up☆
S Popat, P Baas, C Faivre-Finn, N Girard… - Annals of …, 2022 - annalsofoncology.org
Incidence of malignant pleural mesothelioma (MPM) is generally higher in males than
females and is attributed to historical differences in exposures with world-standardised …
females and is attributed to historical differences in exposures with world-standardised …
[HTML][HTML] Durvalumab with platinum-pemetrexed for unresectable pleural mesothelioma: survival, genomic and immunologic analyses from the phase 2 PrE0505 trial
Mesothelioma is a rare and fatal cancer with limited therapeutic options until the recent
approval of combination immune checkpoint blockade. Here we report the results of the …
approval of combination immune checkpoint blockade. Here we report the results of the …
ERS/ESTS/EACTS/ESTRO guidelines for the management of malignant pleural mesothelioma
A Scherpereel, I Opitz, T Berghmans… - European respiratory …, 2020 - Eur Respiratory Soc
The European Respiratory Society (ERS)/European Society of Thoracic Surgeons
(ESTS)/European Association for Cardio-Thoracic Surgery (EACTS)/European Society for …
(ESTS)/European Association for Cardio-Thoracic Surgery (EACTS)/European Society for …
Durvalumab with first-line chemotherapy in previously untreated malignant pleural mesothelioma (DREAM): a multicentre, single-arm, phase 2 trial with a safety run-in
Background There is a strong unmet need to improve systemic therapy in mesothelioma.
Chemotherapy with cisplatin and pemetrexed improves survival in malignant pleural …
Chemotherapy with cisplatin and pemetrexed improves survival in malignant pleural …
Tumour Treating Fields in combination with pemetrexed and cisplatin or carboplatin as first-line treatment for unresectable malignant pleural mesothelioma (STELLAR …
GL Ceresoli, JG Aerts, R Dziadziuszko… - The Lancet …, 2019 - thelancet.com
Summary Background Tumour Treating Fields (TTFields) are a regional, antimitotic
treatment for solid tumours, which is based on the delivery of low-intensity alternating …
treatment for solid tumours, which is based on the delivery of low-intensity alternating …
Gemcitabine with or without ramucirumab as second-line treatment for malignant pleural mesothelioma (RAMES): a randomised, double-blind, placebo-controlled …
C Pinto, PA Zucali, M Pagano, F Grosso… - The Lancet …, 2021 - thelancet.com
Background There is a preclinical rationale for inhibiting angiogenesis in mesothelioma. We
aimed to assess the efficacy and safety of the anti-VEGFR-2 antibody ramucirumab …
aimed to assess the efficacy and safety of the anti-VEGFR-2 antibody ramucirumab …
[HTML][HTML] EURACAN/IASLC proposals for updating the histologic classification of pleural mesothelioma: towards a more multidisciplinary approach
AG Nicholson, JL Sauter, AK Nowak, HL Kindler… - Journal of Thoracic …, 2020 - Elsevier
Introduction Molecular and immunologic breakthroughs are transforming the management of
thoracic cancer, although advances have not been as marked for malignant pleural …
thoracic cancer, although advances have not been as marked for malignant pleural …
New era for malignant pleural mesothelioma: updates on therapeutic options
AS Tsao, HI Pass, A Rimner… - Journal of Clinical …, 2022 - ascopubs.org
Malignant pleural mesothelioma (MPM) is a rare malignancy with few treatment options.
Recent advances have led to US Food and Drug Administration approvals and changes in …
Recent advances have led to US Food and Drug Administration approvals and changes in …