Although intermittent increases in inflammation are critical for survival during physical injury
and infection, recent research has revealed that certain social, environmental and lifestyle …

Hypertension affects approximately one third of the world's adult population and is a major
cause of premature death despite considerable advances in pharmacological treatments …

Hypertension affects 30% of adults and is the leading risk factor for heart attack and stroke.
Traditionally, hypertension has been regarded as a disorder of two systems that are involved …

The pathogenesis of hypertension is known to involve a diverse range of contributing factors
including genetic, environmental, hormonal, hemodynamic and inflammatory forces, to …

The tumor microenvironment (TME) is a unique niche governed by constant crosstalk within
and across all intratumoral cellular compartments. In particular, intratumoral high potassium …

Increasing salt intake has substantial negative impacts on human health and well-being.
This article focused on the construction of Driver-Pressure-State-Impact-Response (DPSIR) …

FOXP3+ regulatory T cells (Tregs) are central for peripheral tolerance, and their
deregulation is associated with autoimmunity. Dysfunctional autoimmune Tregs display pro …

Cellular sodium ion (Na+) homeostasis is integral to organism physiology. Our current
understanding of Na+ homeostasis is largely limited to Na+ transport at the plasma …

The mosaic theory of hypertension was advocated by Irvine Page~ 80 years ago and
suggested that hypertension resulted from the close interactions of different causes …

The Western diet is rich in salt, and a high salt diet (HSD) is suspected to be a risk factor for
cardiovascular diseases. It is now widely accepted that an experimental HSD can stimulate …