Cellular trafficking determines the exon skipping activity of Pip6a-PMO in mdx skeletal and cardiac muscle cells
T Lehto, A Castillo Alvarez, S Gauck… - Nucleic Acids …, 2014 - academic.oup.com
Cell-penetrating peptide-mediated delivery of phosphorodiamidate morpholino oligomers
(PMOs) has shown great promise for exon-skipping therapy of Duchenne Muscular …
(PMOs) has shown great promise for exon-skipping therapy of Duchenne Muscular …
Viral and other cell-penetrating peptides as vectors of therapeutic agents in medicine
Efficient delivery of heterologous molecules for treatment of cells is a great challenge in
modern medicine and pharmacology. Cell-penetrating peptides (CPPs) may improve …
modern medicine and pharmacology. Cell-penetrating peptides (CPPs) may improve …
Mitochondria-based aircraft carrier enhances in vivo imaging of carbon quantum dots and delivery of anticancer drug
The application of engineered bacteria-based drug delivery vehicles to treat cancer has
been practiced for more than a century. Mitochondria, evolutionarily originated from bacteria …
been practiced for more than a century. Mitochondria, evolutionarily originated from bacteria …
Silk as a leading-edge biological macromolecule for improved drug delivery
In recent years, the interest of the researcher's on protein-based biopolymers for drug
delivery has enormously increased. Protein-based drug delivery systems are functionally …
delivery has enormously increased. Protein-based drug delivery systems are functionally …
[PDF][PDF] Homeoprotein signaling in the developing and adult nervous system
A Prochiantz, AA Di Nardo - Neuron, 2015 - cell.com
Signaling classically involves the secretion of diverse molecules that bind specific cell-
surface receptors and engage intracellular transduction cascades. Some exceptions …
surface receptors and engage intracellular transduction cascades. Some exceptions …
MDR in cancer: Addressing the underlying cellular alterations with the use of nanocarriers
Multidrug resistance (MDR) is associated with a wide range of pathological changes at
different cellular and intracellular levels. Nanoparticles (NPs) have been extensively …
different cellular and intracellular levels. Nanoparticles (NPs) have been extensively …
[HTML][HTML] Antisense oligonucleotides for the treatment of cardiomyopathy in Duchenne muscular dystrophy
Q Nguyen, T Yokota - American journal of translational research, 2019 - ncbi.nlm.nih.gov
Duchenne muscular dystrophy (DMD) is an X-linked recessive fatal neuromuscular disorder
characterized by progressive muscle degeneration which affects one in 3500-5000 males …
characterized by progressive muscle degeneration which affects one in 3500-5000 males …
Cell‐penetrating peptides as carriers for oral delivery of biopharmaceuticals
M Kristensen, HM Nielsen - Basic & clinical pharmacology & …, 2016 - Wiley Online Library
Oral delivery of biopharmaceuticals, for example peptides and proteins, constitutes a great
challenge in drug delivery due to their low chemical stability and poor permeation across the …
challenge in drug delivery due to their low chemical stability and poor permeation across the …
Pharmacological modulation of mitochondrial ion channels
The field of mitochondrial ion channels has undergone a rapid development during the last
three decades, due to the molecular identification of some of the channels residing in the …
three decades, due to the molecular identification of some of the channels residing in the …
DNA damage and ovarian ultrastructural lesions induced by nickel oxide nano-particles in Blaps polycresta (Coleoptera: Tenebrionidae)
DAM Kheirallah, LM El-Samad… - Science of the Total …, 2021 - Elsevier
Abstract Nickel oxide nanoparticles (NiO-NPs) have extensively used in industrial and
consumer products. The present study conducted to gain more knowledge about the safe …
consumer products. The present study conducted to gain more knowledge about the safe …