Membrane translocation and organelle-selective delivery steered by polymeric zwitterionic nanospheres

N Morimoto, M Wakamura, K Muramatsu… - …, 2016 - ACS Publications
The majority of nanoparticles designed for cellular delivery of drugs and imaging agents
enter the cell via endocytotic pathways leading to their entrapment in endosomes that …

Non-viral targeted nucleic acid delivery: apply sequences for optimization

Y Wang, E Wagner - Pharmaceutics, 2020 - mdpi.com
In nature, genomes have been optimized by the evolution of their nucleic acid sequences.
The design of peptide-like carriers as synthetic sequences provides a strategy for optimizing …

[HTML][HTML] Distal phenylalanine modification for enhancing cellular delivery of fluorophores, proteins and quantum dots by cell penetrating peptides

EJ Sayers, K Cleal, NG Eissa, P Watson… - Journal of controlled …, 2014 - Elsevier
For cell penetrating peptides (CPPs) to fulfil their promise as effective delivery vectors we
need a better understanding of their mechanisms of cell binding and uptake. This is …

How to evaluate the cellular uptake of CPPs with fluorescence techniques: Dissecting methodological pitfalls associated to tryptophan-rich peptides

Q Seisel, F Pelletier, S Deshayes… - Biochimica et Biophysica …, 2019 - Elsevier
Cell-penetrating peptides (CPP) are broadly recognized as efficient non-viral vectors for the
internalization of compounds such as peptides, oligonucleotides or proteins. Characterizing …

Peptide-conjugated antimiRs improve myotonic dystrophy type 1 phenotypes by promoting endogenous MBNL1 expression

I González-Martínez, E Cerro-Herreros… - … Therapy-Nucleic Acids, 2023 - cell.com
Myotonic dystrophy type 1 (DM1) is a rare neuromuscular disease caused by a CTG repeat
expansion in the DMPK gene that generates toxic RNA with a myriad of downstream …

Activation of cell-penetrating peptides by disulfide bridge formation of truncated precursors

SA Bode, R Wallbrecher, R Brock… - Chemical …, 2014 - pubs.rsc.org
A small library of oligoarginine peptides equipped with terminal cysteines was studied with
respect to their cell-penetrating properties. The peptides themselves were inactive but …

Spectrofluorometric detection of mercury ions in aqueous medium and cellular milieu using MoS2 nanoflakes

P Maiti, S Das, J Panda, D Karmakar, A Pal… - Journal of Physics and …, 2024 - Elsevier
This communication reports the facile hydrothermal synthesis of fluorescent two-dimensional
layered MoS 2 nanoflakes using a biomolecule (l-cysteine) for efficient and sensitive …

Current nanotechnological approaches for an effective delivery of bioactive drug molecules to overcome drug resistance tuberculosis

T Garg, G Rath, RR Murthy, UD Gupta… - Current …, 2015 - ingentaconnect.com
Tuberculosis (TB) is an airborne communicable disease, mainly caused by aerobic, non-
motile, rodshaped, weakly gram-positive, acid-fast tubercular bacillus Mycobacterium …

Synthesis and In Vitro Photodynamic Activities of an Integrin‐Targeting cRGD‐Conjugated Zinc (II) Phthalocyanine

MR Ke, DKP Ng, PC Lo - Chemistry–An Asian Journal, 2014 - Wiley Online Library
Abstract A 1, 4‐disubstituted zinc (II) phthalocyanine conjugated with a cyclic Arg‐Gly‐Asp‐d‐
Phe‐Lys (cRGDfK) moiety through a triazole linker was prepared and characterized by …

Modification of Short Non‐Permeable Peptides to Increase Cellular Uptake and Cytostatic Activity of Their Conjugates

M Yousef, I Szabó, B Biri‐Kovács, B Szeder… - …, 2021 - Wiley Online Library
Cell‐penetrating peptides (CPPs) are well‐known delivery vectors, oligoarginines are an
important class of CPPs, which was modified to increase the cellular uptake and change the …