Delivery of functional proteins into cells may help us understand how specific protein
influences cell behavior as well as treat diseases caused by protein deficiency or loss-of …

In recent decades, bioactive peptides have been gaining recognition in various biomedical
areas, such as intracellular drug delivery (cell-penetrating peptides, CPPs) or anti-infective …

Inhibition of the interaction between the scaffolding protein PSD-95 and the NMDA receptor
has been shown to obstruct ischemic stroke-triggered excitotoxic reactions leading to …

Liposomes are generally used as delivery systems, as they are capable of encapsulating a
wide variety of molecules (ie plasmids, recombinant proteins, therapeutic drugs). However …

Stem cells hold significant clinical potential to treat numerous debilitating diseases and
injures that currently have no treatment plan. While several advances have been made in …

Many studies have been conducted on the development of nanomaterials for medical
applications. The interaction of nanomaterials with human cells is the most important …

Cobra cardiotoxins (CTX) are a family of three-fingered basic polypeptides known to interact
with diverse targets such as heparan sulfates, sulfatides, and integrins on cell surfaces. After …

It is widely accepted that endocytosis mediates the uptake of cationic cell penetrating
peptides (CPPs) at relatively low concentrations (ie nano-to micromolar), while direct …

Cell penetrating peptide (CPP) technologies provide a viable strategy to regulate the
activities of intracellular proteins that may be intractable to other biological agents. In …

The transcriptome of a cell governs the overall cellular expression of proteins, hence,
targeting mRNA holds promise as a therapeutic strategy in the field of drug discovery. RNA …