Estrogen receptor α (ERα) is closely associated with both hormone-dependent and hormone-
independent tumors, and it is also essential for the development of these cancers. The …

Estrogens have been implicated in the pathogenesis of various cancer types, including
colorectal carcinoma (CRC). Estrogen receptors such as ERα and ERβ activate intracellular …

Abstract Immunoglobulin‑like transcript (ILT) 4, a negative regulator of immune response in
allograft rejection, autoimmunity and infectious diseases, has recently been determined to …

The estrogen-related receptor alpha (ERRα) is a primary regulator of mitochondrial energy
metabolism, function and dynamics, and has been implicated in autophagy and immune …

Endocrine disruptors (EDs) belong to large and diverse groups of agents that may cause
multiple biological effects associated with, for example, hormone imbalance and infertility …

Approximately 85% of lung cancer cases are recognized as non‑small cell lung cancer
(NSCLC) with a perilous (13‑17%) 5‑year survival in Europe and the USA. Although tobacco …

Eukaryotic gene expression is under the tight control of transcription factors, which includes
the estrogen-related receptor alpha (ERRα). The endogenous ligand (s) acting as ERRα …

We reported that high estrogen receptor beta (ERβ) expression is independently associated
with better prognosis in female colorectal cancer (CRC) patients. However, estrogen …

Simple Summary Distant metastasis in colorectal cancer still correlates with poor prognosis,
emphasizing the high need for new diagnostic and therapeutic strategies. In the present …

Introduction Sexual dimorphism significantly influences cancer incidence and prognosis.
Notably, females exhibit a lower risk and favorable prognosis for non-reproductive cancers …