The fundamental framework of steroidogenesis is similar across steroidogenic cells,
especially in initial mitochondrial steps. For instance, the START domain containing protein …

Invasion or damage of the male reproductive system is one of the reported outcomes of viral
infection. Current studies have documented that SARS-CoV-2, which causes COVID-19, can …

Over the last decade, the number of cancer survivors has increased thanks to progress in
diagnosis and treatment. Cancer treatments are often accompanied by adverse side effects …

Molecular mechanisms associated with human germ cell aplasia in infertile men remain
undefined. Here we perform single-cell transcriptome profiling to highlight differentially …

Klinefelter syndrome (KS), also known as 47, XXY, is characterized by a distinct set of
physiological abnormalities, commonly including infertility. The molecular basis for …

The testis is pivotal for male reproduction, and its progressive functional decline in aging is
associated with infertility. However, the regulatory mechanism underlying primate testicular …

T-2 mycotoxin, a type A trichothecene toxin that, specifically, causes male and female
reproductive toxicity. We evaluated T-2 toxin toxicity in testes from neonatal testes after in …

The testis is a temperature-sensitive organ that needs to be maintained 2–7° C below core
body temperature to ensure the production of normal sperm. Failure to maintain testicular …

The steroidogenic cells in the testicle, Leydig cells, located in the interstitial compartment,
play a vital role in male reproductive tract development, maintenance of proper …

Microplastics (MPs) are plastic pollutants with a diameter of less than 5 mm and microcystins
(MCs) are natural toxins produced by cyanobacteria. In recent years, the pollution of MPs …