Connecting copper and cancer: from transition metal signalling to metalloplasia
Copper is an essential nutrient whose redox properties make it both beneficial and toxic to
the cell. Recent progress in studying transition metal signalling has forged new links …
the cell. Recent progress in studying transition metal signalling has forged new links …
Copper-induced tumor cell death mechanisms and antitumor theragnostic applications of copper complexes
Y Jiang, Z Huo, X Qi, T Zuo, Z Wu - Nanomedicine, 2022 - Future Medicine
Recent studies found that unbalanced copper homeostasis affect tumor growth, causing
irreversible damage. Copper can induce multiple forms of cell death, including apoptosis …
irreversible damage. Copper can induce multiple forms of cell death, including apoptosis …
Advanced liposome and polymersome-based drug delivery systems: Considerations for physicochemical properties, targeting strategies and stimuli-sensitive …
Liposomes and polymersomes are colloidal vesicles that are self-assembled from lipids and
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …
Copper: an intracellular achilles' heel allowing the targeting of epigenetics, kinase pathways, and cell metabolism in cancer therapeutics
F Michniewicz, F Saletta, JRC Rouaen… - …, 2021 - Wiley Online Library
Copper is an essential transition metal frequently increased in cancer known to strongly
influence essential cellular processes. Targeted therapy protocols utilizing both novel and …
influence essential cellular processes. Targeted therapy protocols utilizing both novel and …
[HTML][HTML] Red blood cell extracellular vesicle-based drug delivery: challenges and opportunities
W Chiangjong, P Netsirisawan, S Hongeng… - Frontiers in …, 2021 - frontiersin.org
Recently, red blood cell-derived extracellular vesicles (RBCEVs) have attracted attention for
clinical applications because of their safety and biocompatibility. RBCEVs can escape …
clinical applications because of their safety and biocompatibility. RBCEVs can escape …
Safety of gold nanoparticles: from in vitro to in vivo testing array checklist
J Lopes, T Ferreira-Gonçalves, L Ascensão, AS Viana… - Pharmaceutics, 2023 - mdpi.com
In recent years, gold nanoparticles (AuNPs) have aroused the interest of many researchers
due to their unique physicochemical and optical properties. AuNPs are being explored in a …
due to their unique physicochemical and optical properties. AuNPs are being explored in a …
[HTML][HTML] Cuproptosis: A novel therapeutic target for overcoming cancer drug resistance
Y Wang, Y Chen, J Zhang, Y Yang, JS Fleishman… - Drug Resistance …, 2023 - Elsevier
Cuproptosis is a newly identified form of cell death driven by copper. Recently, the role of
copper and copper triggered cell death in the pathogenesis of cancers have attracted …
copper and copper triggered cell death in the pathogenesis of cancers have attracted …
Advancing Medicine with Lipid-Based Nanosystems—The Successful Case of Liposomes
Nanomedicine, a promising area of medicine, employs nanosized tools for the diagnosis,
prevention, and treatment of disease. Particularly, liposomes, lipid-based nanovesicles, are …
prevention, and treatment of disease. Particularly, liposomes, lipid-based nanovesicles, are …
Liposomal formulations of a new zinc (II) complex exhibiting high therapeutic potential in a murine colon cancer model
N Ribeiro, M Albino, A Ferreira, C Escrevente… - International Journal of …, 2022 - mdpi.com
Colorectal cancer is the second leading cause of cancer-related mortality. Many current
therapies rely on chemotherapeutic agents with poor specificity for tumor cells. The clinical …
therapies rely on chemotherapeutic agents with poor specificity for tumor cells. The clinical …
[HTML][HTML] Aquaglyceroporin modulators as emergent pharmacological molecules for human diseases
Aquaglyceroporins, a sub-class of aquaporins that facilitate the diffusion of water, glycerol
and other small uncharged solutes across cell membranes, have been recognized for their …
and other small uncharged solutes across cell membranes, have been recognized for their …