Current trends in the development of liposomes for chemotherapeutic drug delivery
Published literature on cancer by health agencies and health organizations reveals
increased cancer incidence year by year. The first line of cancer treatment involves one or …
increased cancer incidence year by year. The first line of cancer treatment involves one or …
Liposomal formulations of a new zinc (II) complex exhibiting high therapeutic potential in a murine colon cancer model
N Ribeiro, M Albino, A Ferreira, C Escrevente… - International Journal of …, 2022 - mdpi.com
Colorectal cancer is the second leading cause of cancer-related mortality. Many current
therapies rely on chemotherapeutic agents with poor specificity for tumor cells. The clinical …
therapies rely on chemotherapeutic agents with poor specificity for tumor cells. The clinical …
Metal coordination and biological screening of a Schiff Base derived from 8-hydroxyquinoline and benzothiazole
Designing new metallodrugs for anticancer therapy is a driving force in the scientific
community. Aiming to contribute to this field, we hereby report the development of a Schiff …
community. Aiming to contribute to this field, we hereby report the development of a Schiff …
Copper and Copper Complexes in Tumor Therapy
Y Wang, T Tang, Y Yuan, N Li, X Wang… - ChemMedChem, 2024 - Wiley Online Library
Copper (Cu), a crucial trace element in physiological processes, has garnered significant
interest for its involvement in cancer progression and potential therapeutic applications. The …
interest for its involvement in cancer progression and potential therapeutic applications. The …
Aquaglyceroporin modulators as emergent pharmacological molecules for human diseases
Aquaglyceroporins, a sub-class of aquaporins that facilitate the diffusion of water, glycerol
and other small uncharged solutes across cell membranes, have been recognized for their …
and other small uncharged solutes across cell membranes, have been recognized for their …
[HTML][HTML] A step forward on the in vitro and in vivo assessment of a novel nanomedicine against melanoma
JO Pinho, M Matias, A Godinho-Santos… - International Journal of …, 2023 - Elsevier
Melanoma is the most aggressive form of skin cancer, with increasing incidence and
mortality rates. To overcome current treatment limitations, a hybrid molecule (HM) combining …
mortality rates. To overcome current treatment limitations, a hybrid molecule (HM) combining …
Blockage of aquaporin‐3 peroxiporin activity by organogold compounds affects melanoma cell adhesion, proliferation and migration
IV da Silva, C Pimpão, I Paccetti‐Alves… - The Journal of …, 2024 - Wiley Online Library
Abstract Aquaporin‐3 (AQP3) is a membrane channel with dual aquaglyceroporin/
peroxiporin activity, facilitating the diffusion of water, glycerol and H2O2 across cell …
peroxiporin activity, facilitating the diffusion of water, glycerol and H2O2 across cell …
Copper Coordination‐Based Nanomedicine for Tumor Theranostics
Y Han, N Xie, W Zhou - Advanced Therapeutics, 2024 - Wiley Online Library
Copper (Cu) is an essential micronutrient for a variety of basic biological processes,
including cell metabolism, proliferation, and angiogenesis. Recently, the concept of …
including cell metabolism, proliferation, and angiogenesis. Recently, the concept of …
Peroxiporins are induced upon oxidative stress insult and are associated with oxidative stress resistance in colon cancer cell lines
Oxidative stress can induce genetic instability and change cellular processes, resulting in
colorectal cancer. Additionally, adaptation of oxidative defense causes therapy resistance, a …
colorectal cancer. Additionally, adaptation of oxidative defense causes therapy resistance, a …
Aquaporin-3 and aquaporin-5 facilitate migration and cell–cell adhesion in pancreatic cancer by modulating cell biomechanical properties
Background: Aquaporins are membrane channels responsible for the bidirectional transfer
of water and small non-charged solutes across cell membranes. AQP3 and AQP5 are …
of water and small non-charged solutes across cell membranes. AQP3 and AQP5 are …