Platelet GPVI (glycoprotein VI) and thrombotic complications in the venous system

G Perrella, M Nagy, SP Watson… - … , and vascular biology, 2021 - Am Heart Assoc
The immunoglobulin receptor GPVI (glycoprotein VI) is selectively expressed on
megakaryocytes and platelets and is currently recognized as a receptor for not only collagen …

Help me, Doctor! My D-dimer is raised

G Lippi, M Franchini, G Targher, EJ Favaloro - Annals of medicine, 2008 - Taylor & Francis
Although optimal strategy for management of patients with suspected venous
thromboembolism depends on local expertise and cost, diagnostic algorithms including …

Long-term prognostic utility of pentraxin 3 and D-dimer as compared to high-sensitivity C-reactive protein and B-type natriuretic peptide in suspected acute coronary …

ØR Mjelva, V Pönitz… - European journal of …, 2016 - academic.oup.com
Background Vascular inflammation plays a key role in the development of atherosclerosis
and acute coronary syndrome (ACS), and pentraxin 3 (PTX3) is one of several novel …

Bivalirudin is a dual inhibitor of thrombin and collagen-dependent platelet activation in patients undergoing percutaneous coronary intervention

C Kimmelstiel, P Zhang, NK Kapur… - Circulation …, 2011 - Am Heart Assoc
Background—Bivalirudin, a direct thrombin inhibitor, is a widely used adjunctive therapy in
patients undergoing percutaneous intervention (PCI). Thrombin is a highly potent agonist of …

[HTML][HTML] Factor XIa and thrombin generation are elevated in patients with acute coronary syndrome and predict recurrent cardiovascular events

R Loeffen, R van Oerle, MPG Leers, JA Kragten… - PLoS …, 2016 - journals.plos.org
Objective In acute coronary syndrome (ACS) cardiac cell damage is preceded by
thrombosis. Therefore, plasma coagulation markers may have additional diagnostic …

Prognostic value of D-dimer and markers of coagulation for stratification of abdominal aortic aneurysm growth

AC Sundermann, K Saum, KA Conrad… - Blood …, 2018 - ashpublications.org
Abdominal aortic aneurysm (AAA) is associated with high morbidity and mortality and is an
established cause of unbalanced hemostasis. A number of hemostatic biomarkers have …

Biomarkers of coagulation and fibrinolysis in acute myocardial infarction: a joint position paper of the Association for Acute CardioVascular Care and the European …

KA Krychtiuk, WS Speidl, E Giannitsis… - … Heart Journal Acute …, 2021 - academic.oup.com
The formation of a thrombus in an epicardial artery may result in an acute myocardial
infarction (AMI). Despite major advances in acute treatment using network approaches to …

Is fibrin formation and thrombin generation increased during and after an acute coronary syndrome?

M Skeppholm, A Kallner, K Malmqvist, M Blombäck… - Thrombosis research, 2011 - Elsevier
INTRODUCTION AND METHODS: In order to study coagulation and fibrinolysis in acute
coronary syndrome (ACS) we used a recently developed assay, called OH-index, which …

Appropriateness of diagnostic strategies for evaluating suspected venous thromboembolism

T Arnason, PS Wells, AJ Forster - Thrombosis and haemostasis, 2007 - thieme-connect.com
It was the objective of this study to determine the proportion of patients who undergo an
appropriate diagnostic work-up following a D-dimer test performed to evaluate suspected …

Haemostatic markers in patients with abdominal aortic aneurysm and the impact of aneurysm size

J Wallinder, D Bergqvist, AE Henriksson - Thrombosis research, 2009 - Elsevier
INTRODUCTION: Abdominal aortic aneurysm is a common condition with high mortality
when rupturing. However, the condition is also associated with nonaneurysmal …