The increasing popularity of 3D cell culture models is being driven by the demand for more
in vivo-like conditions with which to study the biochemistry and biomechanics of numerous …

In vitro model systems have been advanced to recapitulate important physiological features
of the target organ in vivo more closely than the conventional cell line cultures on a petri …

Chimeric antigen receptor (CAR)-T cell therapies have revolutionized cancer treatment,
particularly in hematological malignancies. However, their application to solid tumors is …

Efficiently circumventing the blood-brain barrier (BBB) poses a major hurdle in the
development of drugs that target the central nervous system. Although there are several …

Parkinson's disease (PD) and Alzheimer's disease (AD) are neurodegenerative disorders
caused by the interaction of genetic, environmental, and familial factors. These diseases …

Multiscale printing of 3D perfusable geometries holds great potential for a range of
applications, from microfluidic systems to organ‐on‐a‐chip. However, the generation of …

Incorporating non-invasive biosensing features in organ-on-chip models is of paramount
importance for a wider implementation of these advanced in vitro microfluidic platforms …

Organ on-a-chip (OoC) is a promising technology that aims to recapitulate human body
pathophysiology in a more precise way to advance in drug development and complex …

Because of the brain's complexity, developing effective treatments for neurological disorders
is a formidable challenge. Research efforts to this end are advancing as in vitro systems …

Abstract The human Blood Brain Barrier (hBBB) is a complex cellular architecture separating
the blood from the brain parenchyma. Its integrity and perfect functionality are essential for …