Efficiently circumventing the blood-brain barrier (BBB) poses a major hurdle in the
development of drugs that target the central nervous system. Although there are several …

Parkinson's disease (PD) and Alzheimer's disease (AD) are neurodegenerative disorders
caused by the interaction of genetic, environmental, and familial factors. These diseases …

Multiscale printing of 3D perfusable geometries holds great potential for a range of
applications, from microfluidic systems to organ‐on‐a‐chip. However, the generation of …

Incorporating non-invasive biosensing features in organ-on-chip models is of paramount
importance for a wider implementation of these advanced in vitro microfluidic platforms …

Organ on-a-chip (OoC) is a promising technology that aims to recapitulate human body
pathophysiology in a more precise way to advance in drug development and complex …

This year marks the tenth anniversary of the world's first transplantation of tissue generated
from induced pluripotent stem cells (iPSCs). There is now a growing number of clinical trials …

Because of the brain's complexity, developing effective treatments for neurological disorders
is a formidable challenge. Research efforts to this end are advancing as in vitro systems …

Abstract The human Blood Brain Barrier (hBBB) is a complex cellular architecture separating
the blood from the brain parenchyma. Its integrity and perfect functionality are essential for …

Flexible and stretchable microdevices incorporate highly deformable structures, facilitating
precise functionality at the micro-and millimetre scale. The flexible microdevices have …

The application of microfluidic devices as next-generation cell and tissue culture systems
has increased impressively in the last decades. With that, a plethora of materials as well as …